Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50016895
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174961BDBM50174961((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  0.800nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174963BDBM50174963((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.20nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174967BDBM50174967((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174957BDBM50174957((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174964BDBM50174964((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174956BDBM50174956((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174949BDBM50174949(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi:  1.70nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174955BDBM50174955((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  2.40nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174960BDBM50174960(methyl ((R)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-y...)
Affinity DataKi:  2.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174950BDBM50174950(6-Sulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-...)
Affinity DataKi:  3.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174944BDBM50174944((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  3.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174945BDBM50174945((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  3.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174948BDBM50174948((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  3.90nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174968BDBM50174968((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  4.5nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174962BDBM50174962(methyl (S)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  5.80nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174965BDBM50174965(5-Methylsulfamoyl-2,3-dihydro-benzofuran-2-carboxy...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174952BDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  14nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174947BDBM50174947(methyl (R)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  15nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174943BDBM50174943(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  17nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174966BDBM50174966(6-Methylsulfamoyl-chroman-2-carboxylic acid [(S)-2...)
Affinity DataKi:  19nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174965BDBM50174965(5-Methylsulfamoyl-2,3-dihydro-benzofuran-2-carboxy...)
Affinity DataKi:  25nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174946BDBM50174946(methyl 2-(((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-...)
Affinity DataKi:  31nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174958BDBM50174958((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  31nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174953BDBM50174953(5-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  52nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174954BDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  99nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174959BDBM50174959(methyl ((S)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-y...)
Affinity DataKi:  130nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174956BDBM50174956((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174961BDBM50174961((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174966BDBM50174966(6-Methylsulfamoyl-chroman-2-carboxylic acid [(S)-2...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174951BDBM50174951(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi:  490nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174955BDBM50174955((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 760nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174953BDBM50174953(5-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174948BDBM50174948((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174957BDBM50174957((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174958BDBM50174958((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174950BDBM50174950(6-Sulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174943BDBM50174943(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174968BDBM50174968((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174960BDBM50174960(methyl ((R)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-y...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174947BDBM50174947(methyl (R)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174963BDBM50174963((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174962BDBM50174962(methyl (S)-2-(((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174954BDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174951BDBM50174951(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174949BDBM50174949(N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174968BDBM50174968((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174944BDBM50174944((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174955BDBM50174955((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174952BDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174946BDBM50174946(methyl 2-(((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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