Compile Data Set for Download or QSAR
maximum 50k data
Found 74 Enz. Inhib. hit(s) with all data for entry = 50016895
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174961((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  0.800nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174963((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.20nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174967((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174957((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174964((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174956((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174949(CHEMBL371685 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi:  1.70nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174955((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  2.40nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174960(CHEMBL197070 | methyl ((R)-2-(((S)-2-((S)-3-hydrox...)
Affinity DataKi:  2.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174950(6-Sulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-...)
Affinity DataKi:  3.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174944((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  3.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174945((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  3.60nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174948((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  3.90nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174968((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  4.5nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174962(CHEMBL197126 | methyl (S)-2-(((S)-2-((S)-3-hydroxy...)
Affinity DataKi:  5.80nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  14nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174947(CHEMBL198487 | methyl (R)-2-(((S)-2-((S)-3-hydroxy...)
Affinity DataKi:  15nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174943(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  17nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174966(6-Methylsulfamoyl-chroman-2-carboxylic acid [(S)-2...)
Affinity DataKi:  19nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174965(5-Methylsulfamoyl-2,3-dihydro-benzofuran-2-carboxy...)
Affinity DataKi:  25nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174958((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  31nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174946(CHEMBL197293 | methyl 2-(((S)-2-((S)-3-hydroxypyrr...)
Affinity DataKi:  31nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174953(5-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi:  52nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  99nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174959(CHEMBL196813 | methyl ((S)-2-(((S)-2-((S)-3-hydrox...)
Affinity DataKi:  130nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174951(CHEMBL200478 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi:  490nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174943(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174946(CHEMBL197293 | methyl 2-(((S)-2-((S)-3-hydroxypyrr...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174947(CHEMBL198487 | methyl (R)-2-(((S)-2-((S)-3-hydroxy...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174951(CHEMBL200478 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174953(5-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174956((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174949(CHEMBL371685 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174951(CHEMBL200478 | N-((S)-2-((S)-3-hydroxypyrrolidin-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174954((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174953(5-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174956((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174945((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174959(CHEMBL196813 | methyl ((S)-2-(((S)-2-((S)-3-hydrox...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174958((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174960(CHEMBL197070 | methyl ((R)-2-(((S)-2-((S)-3-hydrox...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174961((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174946(CHEMBL197293 | methyl 2-(((S)-2-((S)-3-hydroxypyrr...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174955((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174966(6-Methylsulfamoyl-chroman-2-carboxylic acid [(S)-2...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174965(5-Methylsulfamoyl-2,3-dihydro-benzofuran-2-carboxy...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174968((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174943(6-acetamido-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl...)
Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50174965(5-Methylsulfamoyl-2,3-dihydro-benzofuran-2-carboxy...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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