Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 1949
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15393(CHEMBL200469 | 3-(5-chloro-2,4-dihydroxyphenyl)-N-...)
Affinity DataIC50: 258nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15399(CHEMBL200255 | 3-(5-chloro-2,4-dihydroxyphenyl)-N-...)
Affinity DataIC50: 461nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15397(3-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-fluoropheny...)
Affinity DataIC50: 5.35E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15398(3-(5-chloro-2,4-dihydroxyphenyl)-N-{[3-(trifluorom...)
Affinity DataIC50: 5.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15389(3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-methoxypheny...)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15395(3-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-methoxyphen...)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15390(3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-chlorophenyl...)
Affinity DataIC50: 6.90E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15386(3-(5-chloro-2,4-dihydroxyphenyl)-N-phenyl-1H-pyraz...)
Affinity DataIC50: 7.10E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15396(3-(5-chloro-2,4-dihydroxyphenyl)-N-[(3-methoxyphen...)
Affinity DataIC50: 1.07E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15388(3-(5-chloro-2,4-dihydroxyphenyl)-N-(3-methoxypheny...)
Affinity DataIC50: 1.17E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15394(N-benzyl-3-(5-chloro-2,4-dihydroxyphenyl)-1H-pyraz...)
Affinity DataIC50: 1.28E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15387(3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-hydroxypheny...)
Affinity DataIC50: 1.47E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15392(3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-acetamidophe...)
Affinity DataIC50: 3.15E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15400(3-(5-chloro-2,4-dihydroxyphenyl)-N-(furan-2-ylmeth...)
Affinity DataIC50: 3.56E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15401(3-(5-chloro-2,4-dihydroxyphenyl)-N-(pyridin-2-yl)-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15391(3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-methoxypheny...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed