Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50016912
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175173BDBM50175173(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL10 (IP-10)-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175193BDBM50175193(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175173BDBM50175173(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175176BDBM50175176(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-fluor...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175183BDBM50175183(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175168BDBM50175168(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175187BDBM50175187(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-benzamid...)
Affinity DataIC50: 70nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175170BDBM50175170(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-cyano...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175173BDBM50175173(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CXCL11-induced CXCR3 mediated T-cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175178BDBM50175178(4-(4-((4-chlorophenethyl)carbamoyl)-2-(3-chloroben...)
Affinity DataIC50: 120nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175169BDBM50175169(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophe...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175185BDBM50175185(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-metho...)
Affinity DataIC50: 170nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175164BDBM50175164(4-(4-((2-chlorophenethyl)carbamoyl)-2-(3-chloroben...)
Affinity DataIC50: 190nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175161BDBM50175161(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(4-fluor...)
Affinity DataIC50: 200nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175190BDBM50175190(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,5-dif...)
Affinity DataIC50: 240nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175165BDBM50175165(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(isonico...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175177BDBM50175177(4-(4-((4-chlorobenzyl)carbamoyl)-2-(3-chlorobenzam...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175182BDBM50175182(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,4-dif...)
Affinity DataIC50: 290nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175192BDBM50175192(4-(4-((3-chlorophenethyl)carbamoyl)-2-(3-chloroben...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175166BDBM50175166(4-(4-((4-fluorophenethyl)carbamoyl)-2-(3-chloroben...)
Affinity DataIC50: 320nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175188BDBM50175188(4-(4-((3-fluorophenethyl)carbamoyl)-2-(3-chloroben...)
Affinity DataIC50: 340nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175191BDBM50175191(4-(4-((2-fluorophenethyl)carbamoyl)-2-(3-chloroben...)
Affinity DataIC50: 340nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175163BDBM50175163(4-(4-((3,4-dimethoxyphenethyl)carbamoyl)-2-(3-chlo...)
Affinity DataIC50: 420nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175174BDBM50175174(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophe...)
Affinity DataIC50: 490nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175171BDBM50175171(4-(2-(3-chlorobenzamido)-4-(phenethylcarbamoyl)phe...)
Affinity DataIC50: 510nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175175BDBM50175175(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(2-fluor...)
Affinity DataIC50: 590nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175172BDBM50175172(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(furan-2...)
Affinity DataIC50: 640nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175184BDBM50175184(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(2-chlor...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175181BDBM50175181(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175179BDBM50175179(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)
Affinity DataIC50: 890nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175189BDBM50175189(4-(4-(benzylcarbamoyl)-2-(3-chlorobenzamido)phenyl...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175162BDBM50175162(4-(2-(3-chlorobenzamido)-4-((cyclopropylmethyl)car...)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175160BDBM50175160(4-(2-(3-chlorobenzamido)-4-(isopropylcarbamoyl)phe...)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175180BDBM50175180(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(nicotin...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175167BDBM50175167(methyl 4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175186BDBM50175186(ethyl 4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed