Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50016935
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175564BDBM50175564(N-Hydroxy-2-(7-oxo-7,8-dihydro-6H-quinolizine-4-su...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175542BDBM50175542(7-Oxo-7,8-dihydro-6H-quinolizine-4-carboxylic acid...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175534BDBM50175534(N-Hydroxy-3-(7-oxo-7,8-dihydro-6H-quinolizine-4-su...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175544BDBM50175544(N-Hydroxy-4-oxo-4-(4-trifluoromethyl-phenyl)-butyr...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175531BDBM50175531(N-Hydroxy-2-(4-trifluoromethyl-benzenesulfonylamin...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175561BDBM50175561(N-Hydroxy-3-(4-trifluoromethyl-benzenesulfonyl)-pr...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175545BDBM50175545(N-Hydroxycarbamoylmethyl-4-trifluoromethyl-benzami...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175528BDBM50175528(N-Hydroxy-4-oxo-4-(7-oxo-7,8-dihydro-6H-quinolizin...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175529BDBM50175529(N-Hydroxy-3-[4-(pyridin-4-yloxy)-benzenesulfonyl]-...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175557BDBM50175557(N-Hydroxy-2-[4-(pyridin-4-yloxy)-benzenesulfonylam...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175541BDBM50175541(N-Hydroxycarbamoylmethyl-4-(pyridin-4-yloxy)-benza...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175550BDBM50175550(N-Hydroxy-4-oxo-4-[4-(pyridin-4-yloxy)-phenyl]-but...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175532BDBM50175532(3-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175556BDBM50175556(2-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175559BDBM50175559(4-[4-(4-Fluoro-2-methyl-benzyloxy)-phenyl]-N-hydro...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175553BDBM50175553(4-(4-Fluoro-2-methyl-benzyloxy)-N-hydroxycarbamoyl...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175548BDBM50175548(N-Hydroxy-2-(4-phenoxy-benzenesulfonylamino)-aceta...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175558BDBM50175558(N-Hydroxycarbamoylmethyl-4-phenoxy-benzamide | CHE...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175549BDBM50175549(N-Hydroxy-4-oxo-4-(4-phenoxy-phenyl)-butyramide | ...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175565BDBM50175565(N-Hydroxy-3-(4-phenoxy-benzenesulfonyl)-propionami...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175551BDBM50175551(N-Hydroxy-4-(4-methoxy-phenyl)-4-oxo-butyramide | ...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11328BDBM11328(CHEMBL83508 | N-hydroxy-2-[(4-methoxybenzene)sulfo...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175543BDBM50175543(N-Hydroxy-3-(4-methoxy-benzenesulfonyl)-propionami...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175547BDBM50175547(N-Hydroxycarbamoylmethyl-4-methoxy-benzamide | CHE...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175527BDBM50175527(2-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175540BDBM50175540(4-(4-Chloro-phenoxy)-N-hydroxycarbamoylmethyl-benz...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175536BDBM50175536(3-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-N-hydroxy...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175554BDBM50175554(4-[4-(4-Chloro-phenoxy)-phenyl]-N-hydroxy-4-oxo-bu...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175562BDBM50175562(N-Hydroxycarbamoylmethyl-4-prop-1-ynyloxy-benzamid...)
Affinity DataIC50: 121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175563BDBM50175563(N-Hydroxy-3-(4-prop-1-ynyloxy-benzenesulfonyl)-pro...)
Affinity DataIC50: 121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175552BDBM50175552(N-Hydroxy-4-oxo-4-(4-prop-1-ynyloxy-phenyl)-butyra...)
Affinity DataIC50: 121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175537BDBM50175537(N-Hydroxy-2-(4-prop-1-ynyloxy-benzenesulfonylamino...)
Affinity DataIC50: 121nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175530BDBM50175530(4-(4-Imidazol-1-yl-phenoxy)-piperidine-1-carboxyli...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175546BDBM50175546(N-Hydroxy-2-[4-(4-imidazol-1-yl-phenoxy)-piperidin...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175539BDBM50175539(N-Hydroxy-3-[4-(4-imidazol-1-yl-phenoxy)-piperidin...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175538BDBM50175538(N-Hydroxy-4-[4-(4-imidazol-1-yl-phenoxy)-piperidin...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175533BDBM50175533(3-(4-Butoxy-benzenesulfonyl)-N-hydroxy-propionamid...)
Affinity DataIC50: 920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175560BDBM50175560(4-(4-Butoxy-phenyl)-N-hydroxy-4-oxo-butyramide | C...)
Affinity DataIC50: 920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175555BDBM50175555(4-Butoxy-N-hydroxycarbamoylmethyl-benzamide | CHEM...)
Affinity DataIC50: 920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
De Novo Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175535BDBM50175535(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Affinity DataIC50: 920nMAssay Description:Inhibitory concentration against (MMP-1) matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed