Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50016945
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175644(CHEMBL200044 | methyl 3-(4-(furan-2-yl)phenyl)-8-a...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175634(CHEMBL200698 | methyl 3-(4-(furan-3-yl)phenyl)-8-m...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175646(3-(3',5'-difluoro-biphenyl-4-yl)-8-methyl-8-aza-bi...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175640(3-(3'-fluoro-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175648(CHEMBL199704 | methyl 3-(4-(furan-2-yl)phenyl)-8-m...)
Affinity DataKi:  1.13nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175642(CHEMBL199743 | methyl 3-(4-(5-methoxypyridin-3-yl)...)
Affinity DataKi:  1.56nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175647(CHEMBL382943 | methyl 8-methyl-3-(4-(thiazol-2-yl)...)
Affinity DataKi:  1.67nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175643(CHEMBL199634 | methyl 8-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataKi:  3.51nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175644(CHEMBL200044 | methyl 3-(4-(furan-2-yl)phenyl)-8-a...)
Affinity DataKi:  3.76nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175639(CHEMBL199850 | methyl 3-(4-(5-methoxypyridin-3-yl)...)
Affinity DataKi:  3.91nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175636(CHEMBL381418 | methyl 3-(4-(thiazol-2-yl)phenyl)-8...)
Affinity DataKi:  5.15nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175648(CHEMBL199704 | methyl 3-(4-(furan-2-yl)phenyl)-8-m...)
Affinity DataKi:  7.14nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175637(CHEMBL383572 | methyl 8-methyl-3-(4-(pyrazin-2-yl)...)
Affinity DataKi:  11.3nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175644(CHEMBL200044 | methyl 3-(4-(furan-2-yl)phenyl)-8-a...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175634(CHEMBL200698 | methyl 3-(4-(furan-3-yl)phenyl)-8-m...)
Affinity DataKi:  14.2nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175649(CHEMBL199512 | methyl 8-methyl-3-(4-(quinolin-3-yl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175640(3-(3'-fluoro-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  25.2nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175643(CHEMBL199634 | methyl 8-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataKi:  26.1nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175646(3-(3',5'-difluoro-biphenyl-4-yl)-8-methyl-8-aza-bi...)
Affinity DataKi:  31.7nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175635(CHEMBL372121 | methyl 8-methyl-3-(4-(pyrimidin-5-y...)
Affinity DataKi:  33.1nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175645(CHEMBL199407 | methyl 8-methyl-3-(4-(pyridin-2-yl)...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175649(CHEMBL199512 | methyl 8-methyl-3-(4-(quinolin-3-yl...)
Affinity DataKi:  59.8nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175636(CHEMBL381418 | methyl 3-(4-(thiazol-2-yl)phenyl)-8...)
Affinity DataKi:  69.6nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175646(3-(3',5'-difluoro-biphenyl-4-yl)-8-methyl-8-aza-bi...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175637(CHEMBL383572 | methyl 8-methyl-3-(4-(pyrazin-2-yl)...)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175634(CHEMBL200698 | methyl 3-(4-(furan-3-yl)phenyl)-8-m...)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175645(CHEMBL199407 | methyl 8-methyl-3-(4-(pyridin-2-yl)...)
Affinity DataKi:  161nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175637(CHEMBL383572 | methyl 8-methyl-3-(4-(pyrazin-2-yl)...)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175636(CHEMBL381418 | methyl 3-(4-(thiazol-2-yl)phenyl)-8...)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175640(3-(3'-fluoro-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  249nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175642(CHEMBL199743 | methyl 3-(4-(5-methoxypyridin-3-yl)...)
Affinity DataKi:  332nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175635(CHEMBL372121 | methyl 8-methyl-3-(4-(pyrimidin-5-y...)
Affinity DataKi:  344nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175647(CHEMBL382943 | methyl 8-methyl-3-(4-(thiazol-2-yl)...)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175641(3-(3'-dimethylamino-biphenyl-4-yl)-8-methyl-8-aza-...)
Affinity DataKi:  545nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175639(CHEMBL199850 | methyl 3-(4-(5-methoxypyridin-3-yl)...)
Affinity DataKi:  587nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175642(CHEMBL199743 | methyl 3-(4-(5-methoxypyridin-3-yl)...)
Affinity DataKi:  739nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175638(CHEMBL199451 | methyl 8-methyl-3-(4-(pyridin-4-yl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175641(3-(3'-dimethylamino-biphenyl-4-yl)-8-methyl-8-aza-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175648(CHEMBL199704 | methyl 3-(4-(furan-2-yl)phenyl)-8-m...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175643(CHEMBL199634 | methyl 8-methyl-3-(4-(pyridin-3-yl)...)
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50175638(CHEMBL199451 | methyl 8-methyl-3-(4-(pyridin-4-yl)...)
Affinity DataKi:  1.57E+3nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175639(CHEMBL199850 | methyl 3-(4-(5-methoxypyridin-3-yl)...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175645(CHEMBL199407 | methyl 8-methyl-3-(4-(pyridin-2-yl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175647(CHEMBL382943 | methyl 8-methyl-3-(4-(thiazol-2-yl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175635(CHEMBL372121 | methyl 8-methyl-3-(4-(pyrimidin-5-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175638(CHEMBL199451 | methyl 8-methyl-3-(4-(pyridin-4-yl)...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175649(CHEMBL199512 | methyl 8-methyl-3-(4-(quinolin-3-yl...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50175641(3-(3'-dimethylamino-biphenyl-4-yl)-8-methyl-8-aza-...)
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed