Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50037627
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against Pregnane X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against Pregnane X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataKi:  37nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataKi:  39nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataKi:  201nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataKi:  224nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataKi:  224nMAssay Description:Inhibitory concentration against Glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataKi:  240nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataKi:  252nMAssay Description:Inhibitory concentration against Glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataKi:  315nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50: 660nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50: 740nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibitory concentration against Glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50: 6.06E+3nMAssay Description:Inhibitory concentration against Glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Farnesoid X receptor; range from 50-100000More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Farnesoid X receptor; range from 50-100000More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed