Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50017003
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176285BDBM50176285(ethyl 6,6-dimethyl-2-(3-(pyridin-2-ylsulfonyl)urei...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176286BDBM50176286(ethyl 6,6-dimethyl-2-(3-(2-(trifluoromethyl)phenyl...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176297BDBM50176297(ethyl 6,6-dimethyl-2-(3-(1-methyl-1H-pyrazol-5-yls...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176296BDBM50176296(ethyl 6,6-dimethyl-2-(3-(pyrimidin-2-ylsulfonyl)ur...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176295BDBM50176295(ethyl 6,6-dimethyl-2-(3-(5-methylpyridin-2-ylsulfo...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176301BDBM50176301(ethyl 2-(3-(4-fluorophenylsulfonyl)ureido)-6,6-dim...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176282BDBM50176282(ethyl 6,6-dimethyl-2-(3-(1-methyl-1H-imidazol-2-yl...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176283BDBM50176283(ethyl 6,6-dimethyl-2-(3-tosylureido)-4,5,6,7-tetra...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176280BDBM50176280(ethyl 6,6-dimethyl-2-(3-(phenylsulfonyl)ureido)-4,...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176293BDBM50176293(ethyl 2-(3-(4-cyanophenylsulfonyl)ureido)-6,6-dime...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176303BDBM50176303(ethyl 2-(3-(3,4-dihydroisoquinolin-2(1H)-ylsulfony...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176291BDBM50176291(ethyl 6,6-dimethyl-2-(3-(2-(trifluoromethoxy)pheny...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176285BDBM50176285(ethyl 6,6-dimethyl-2-(3-(pyridin-2-ylsulfonyl)urei...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176282BDBM50176282(ethyl 6,6-dimethyl-2-(3-(1-methyl-1H-imidazol-2-yl...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176286BDBM50176286(ethyl 6,6-dimethyl-2-(3-(2-(trifluoromethyl)phenyl...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176280BDBM50176280(ethyl 6,6-dimethyl-2-(3-(phenylsulfonyl)ureido)-4,...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176295BDBM50176295(ethyl 6,6-dimethyl-2-(3-(5-methylpyridin-2-ylsulfo...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176308BDBM50176308(ethyl 6-methyl-2-(3-tosylureido)-4,5,6,7-tetrahydr...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176277BDBM50176277(ethyl 6,6-dimethyl-2-(3-(pyrrolidin-1-ylsulfonyl)u...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176289BDBM50176289(ethyl 6,6-dimethyl-2-(3-(piperidin-1-ylsulfonyl)ur...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176294BDBM50176294(ethyl 2-(3-(indolin-1-ylsulfonyl)ureido)-6,6-dimet...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176297BDBM50176297(ethyl 6,6-dimethyl-2-(3-(1-methyl-1H-pyrazol-5-yls...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176294BDBM50176294(ethyl 2-(3-(indolin-1-ylsulfonyl)ureido)-6,6-dimet...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176290BDBM50176290(ethyl 6,6-dimethyl-2-(3-(morpholinosulfonyl)ureido...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176296BDBM50176296(ethyl 6,6-dimethyl-2-(3-(pyrimidin-2-ylsulfonyl)ur...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176279BDBM50176279(ethyl 2-(3-(4-acetylpiperazin-1-ylsulfonyl)ureido)...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176277BDBM50176277(ethyl 6,6-dimethyl-2-(3-(pyrrolidin-1-ylsulfonyl)u...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176291BDBM50176291(ethyl 6,6-dimethyl-2-(3-(2-(trifluoromethoxy)pheny...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176288BDBM50176288(ethyl 6,6-dimethyl-2-(3-(4-methylpiperazin-1-ylsul...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176283BDBM50176283(ethyl 6,6-dimethyl-2-(3-tosylureido)-4,5,6,7-tetra...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176293BDBM50176293(ethyl 2-(3-(4-cyanophenylsulfonyl)ureido)-6,6-dime...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176281BDBM50176281(ethyl 2-(3-(azepan-1-ylsulfonyl)ureido)-6,6-dimeth...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176301BDBM50176301(ethyl 2-(3-(4-fluorophenylsulfonyl)ureido)-6,6-dim...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176307BDBM50176307(ethyl 5-methyl-2-(3-tosylureido)-4,5,6,7-tetrahydr...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176303BDBM50176303(ethyl 2-(3-(3,4-dihydroisoquinolin-2(1H)-ylsulfony...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176279BDBM50176279(ethyl 2-(3-(4-acetylpiperazin-1-ylsulfonyl)ureido)...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176309BDBM50176309(ethyl 2-(3-(naphthalen-1-ylsulfonyl)ureido)-4,5,6,...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176287BDBM50176287(ethyl 2-(3-(phenylsulfonyl)ureido)-4,5,6,7-tetrahy...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176284BDBM50176284(ethyl 2-(3-(o-tolylsulfonyl)ureido)-4,5,6,7-tetrah...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176302BDBM50176302(ethyl 2-(3-(m-tolylsulfonyl)ureido)-4,5,6,7-tetrah...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176300BDBM50176300(ethyl 2-(3-tosylureido)-4,5,6,7-tetrahydrobenzo[b]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176298BDBM50176298(ethyl 2-(3-(4-chlorophenylsulfonyl)ureido)-4,5,6,7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176289BDBM50176289(ethyl 6,6-dimethyl-2-(3-(piperidin-1-ylsulfonyl)ur...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176281BDBM50176281(ethyl 2-(3-(azepan-1-ylsulfonyl)ureido)-6,6-dimeth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176305BDBM50176305(ethyl 2-(3-(3-methoxyphenylsulfonyl)ureido)-4,5,6,...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176292BDBM50176292(ethyl 2-(3-(4-fluorophenylsulfonyl)ureido)-4,5,6,7...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176288BDBM50176288(ethyl 6,6-dimethyl-2-(3-(4-methylpiperazin-1-ylsul...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176278BDBM50176278(ethyl 4-methyl-2-(3-tosylureido)-4,5,6,7-tetrahydr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176290BDBM50176290(ethyl 6,6-dimethyl-2-(3-(morpholinosulfonyl)ureido...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against delta-21 C-terminally truncated HCV 1b (BB7 isolate) RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Viropharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176306BDBM50176306(ethyl 2-(3-(4-nitrophenylsulfonyl)ureido)-4,5,6,7-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against HCV 4a NS5B full length RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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