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Found 34 Enz. Inhib. hit(s) with all data for entry = 50017090
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against cdc25B phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against CD45 phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177324(2-(4-(7-pentadecanoylcyclopenta[d][1,2]oxazin-4-yl...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against YOP protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against LAR protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibitory activity against YOP protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibitory activity against CD45 phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibitory activity against cdc25A phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177322(2-(2,6-dibromo-4-(7-(4-methoxybenzoyl)cyclopenta[d...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177320(2-(4-(7-(3-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibitory activity against cdc25C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177319((2,4-dichlorophenyl)(4-(4-methoxyphenyl)cyclopenta...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177326(1-(4-benzylpiperazin-1-yl)-2-(4-(7-(4-methoxybenzo...)
Affinity DataIC50:  5.48E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177325(2-(4-(7-(2-(4-methoxyphenyl)acetyl)cyclopenta[d][1...)
Affinity DataIC50:  5.63E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  5.71E+3nMAssay Description:Inhibitory activity against YOP protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177321(2-(4-(7-(3-(trifluoromethyl)benzoyl)cyclopenta[d][...)
Affinity DataIC50:  7.55E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177327((S)-2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]ox...)
Affinity DataIC50:  7.82E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177323(2-(4-(7-(cyclopentanecarbonyl)cyclopenta[d][1,2]ox...)
Affinity DataIC50:  8.19E+3nMAssay Description:Inhibitory activity against recombinant human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against LAR protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against cdc25C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against cdc25B phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against cdc25A phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibitory activity against cdc25B phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibitory activity against CD45 phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  3.52E+4nMAssay Description:Inhibitory activity against Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  6.17E+4nMAssay Description:Inhibitory activity against LAR protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  6.17E+4nMAssay Description:Inhibitory activity against cdc25C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  7.33E+4nMAssay Description:Inhibitory activity against cdc25A phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)
Affinity DataIC50:  1.81E+5nMAssay Description:Inhibitory activity against VH1-related phosphatase VHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed