Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 2284
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 0.240nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 0.260nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 1.10nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18916(2-{4-[3-bromo-4-(2-methylbutanamido)phenoxy]-3,5-d...)
Affinity DataIC50: 4.30nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50: 13nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18918(2-{4-[3-bromo-4-(2-ethylbutanamido)phenoxy]-3,5-di...)
Affinity DataIC50: 16nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18915(2-{4-[3-bromo-4-(2-methylpropanamido)phenoxy]-3,5-...)
Affinity DataIC50: 18nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 25nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18919(2-{4-[3-bromo-4-(2-propylpentanamido)phenoxy]-3,5-...)
Affinity DataIC50: 45nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18917(2-{4-[3-bromo-4-(2-methylpentanamido)phenoxy]-3,5-...)
Affinity DataIC50: 47nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18914(2-[4-(3-bromo-4-propanamidophenoxy)-3,5-dichloroph...)
Affinity DataIC50: 140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18916(2-{4-[3-bromo-4-(2-methylbutanamido)phenoxy]-3,5-d...)
Affinity DataIC50: 240nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18918(2-{4-[3-bromo-4-(2-ethylbutanamido)phenoxy]-3,5-di...)
Affinity DataIC50: 610nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18915(2-{4-[3-bromo-4-(2-methylpropanamido)phenoxy]-3,5-...)
Affinity DataIC50: 630nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18919(2-{4-[3-bromo-4-(2-propylpentanamido)phenoxy]-3,5-...)
Affinity DataIC50: 1.20E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18917(2-{4-[3-bromo-4-(2-methylpentanamido)phenoxy]-3,5-...)
Affinity DataIC50: 1.30E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18914(2-[4-(3-bromo-4-propanamidophenoxy)-3,5-dichloroph...)
Affinity DataIC50: 3.30E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed