Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50017192
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50164047BDBM50164047(N-[2,2']bithiophenyl-5-ylmethyl-N'-(2'-sulfamoyl-b...)
Affinity DataKi:  150nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178865BDBM50178865(trans-N-benzyl-2-(1-hydroxy-3-(3-(trifluoromethoxy...)
Affinity DataKi:  230nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178861BDBM50178861(trans-N1-methyl-N1-((2'-sulfamoylbiphenyl-4-yl)met...)
Affinity DataKi:  290nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178859BDBM50178859(trans-N-benzyl-2-(1-hydroxy-3-(2-(trifluoromethoxy...)
Affinity DataKi:  320nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178867BDBM50178867(N-((trans-2-(1-hydroxy-3-phenylpropyl)cyclopentyl)...)
Affinity DataKi:  330nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178863BDBM50178863(trans-N-benzyl-2-((S)-1-hydroxy-3-(4-(trifluoromet...)
Affinity DataKi:  360nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178854BDBM50178854(trans-N-(2-(trifluoromethyl)benzyl)-2-(1-hydroxy-3...)
Affinity DataKi:  440nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178853BDBM50178853(trans-N-(3,5-dichlorobenzyl)-2-(1-hydroxy-3-(3-(tr...)
Affinity DataKi:  440nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178864BDBM50178864(N-((trans-2-(1-hydroxy-3-phenylpropyl)cyclopentyl)...)
Affinity DataKi:  630nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178851BDBM50178851(1-(trans-2-((4-(trifluoromethoxy)benzyloxy)methyl)...)
Affinity DataKi:  820nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178868BDBM50178868(trans-N-(3,5-dichlorobenzyl)-2-(1-hydroxy-3-(4-(tr...)
Affinity DataKi:  870nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178869BDBM50178869(trans-N-(3,5-dichlorobenzyl)-2-(1-hydroxy-3-phenyl...)
Affinity DataKi:  980nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178856BDBM50178856(1-(trans-2-((3,5-dichlorobenzyloxy)methyl)cyclopen...)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178857BDBM50178857(trans-N-(3,5-dichlorobenzyl)-2-(1-hydroxy-3-(2-(tr...)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178855BDBM50178855(trans-N-(3,5-dichlorobenzyl)-2-(1-hydroxy-3-(4-met...)
Affinity DataKi:  1.21E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178870BDBM50178870(trans-N1-(4-(trifluoromethoxy)benzyl)-N2-benzyl-N2...)
Affinity DataKi:  1.49E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178866BDBM50178866(trans-N-benzyl-2-(1-hydroxy-3-phenylpropyl)cyclope...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178850BDBM50178850(1-(trans-2-(3,5-dichlorophenethoxy)cyclopentyl)-3-...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178858BDBM50178858(1-(trans-2-(4-(trifluoromethoxy)phenethoxy)cyclope...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178862BDBM50178862(3,5-dichloro-N-((trans-2-(1-hydroxy-3-phenylpropyl...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178852BDBM50178852(trans-N-(4-(trifluoromethoxy)benzyl)-2-(1-hydroxy-...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178860BDBM50178860(3,5-dichloro-N-((trans-2-(1-hydroxy-3-phenylpropyl...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of peripheral nerve sodium channel NaV1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed