Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50017196
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178922(7-(4-(aminomethyl)phenyl)-9-cyclopropyl-6-fluorois...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178926(9-cyclopropyl-6-fluoro-7-(piperazin-1-yl)isothiazo...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178928(7-(3-(aminomethyl)phenyl)-9-cyclopropyl-6-fluorois...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178928(7-(3-(aminomethyl)phenyl)-9-cyclopropyl-6-fluorois...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178924(9-cyclopropyl-6-fluoro-7-(3-hydroxyphenyl)isothiaz...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178923(7-(3-amino-4-fluorophenyl)-9-cyclopropyl-6-fluoroi...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178919(7-(4-aminophenyl)-9-cyclopropyl-6-fluoroisothiazol...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178917(CHEMBL430 | 7-(3-(aminomethyl)-4-(methoxyimino)pyr...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178917(CHEMBL430 | 7-(3-(aminomethyl)-4-(methoxyimino)pyr...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178918(9-cyclopropyl-6-fluoro-7-(3-(hydroxymethyl)phenyl)...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178926(9-cyclopropyl-6-fluoro-7-(piperazin-1-yl)isothiazo...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117914(1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpipera...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178925(9-cyclopropyl-6-fluoro-7-(3-(piperidin-2-yl)phenyl...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178921(9-cyclopropyl-6-fluoro-7-(4-hydroxyphenyl)isothiaz...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178916(9-cyclopropyl-6-fluoro-7-(4-(hydroxymethyl)phenyl)...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178920(9-cyclopropyl-6-fluoro-7-(3-fluorophenyl)isothiazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178929(9-cyclopropyl-6-fluoro-7-(4-(piperidin-2-yl)phenyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117914(1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpipera...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178922(7-(4-(aminomethyl)phenyl)-9-cyclopropyl-6-fluorois...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178924(9-cyclopropyl-6-fluoro-7-(3-hydroxyphenyl)isothiaz...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178929(9-cyclopropyl-6-fluoro-7-(4-(piperidin-2-yl)phenyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178925(9-cyclopropyl-6-fluoro-7-(3-(piperidin-2-yl)phenyl...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178927(7-(3-aminophenyl)-9-cyclopropyl-6-fluoroisothiazol...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178920(9-cyclopropyl-6-fluoro-7-(3-fluorophenyl)isothiazo...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178918(9-cyclopropyl-6-fluoro-7-(3-(hydroxymethyl)phenyl)...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178923(7-(3-amino-4-fluorophenyl)-9-cyclopropyl-6-fluoroi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178927(7-(3-aminophenyl)-9-cyclopropyl-6-fluoroisothiazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178919(7-(4-aminophenyl)-9-cyclopropyl-6-fluoroisothiazol...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178921(9-cyclopropyl-6-fluoro-7-(4-hydroxyphenyl)isothiaz...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178916(9-cyclopropyl-6-fluoro-7-(4-(hydroxymethyl)phenyl)...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed