Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50017240
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179446((S)-4,4-dimethyl-2-oxo-1-((4-(trifluoromethyl)phen...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179439((S)-1-(benzo[d]thiazole-2-carbonyl)-4,4-dimethyl-2...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179454((S)-4,4-dimethyl-2-oxo-1-(2-(trifluoromethyl)-1,3,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179458((S)-1-(2-naphthoyl)-4,4-dimethyl-2-oxopyrrolidin-3...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179438((S)-1-(1H-indole-5-carbonyl)-4,4-dimethyl-2-oxopyr...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179437((S)-4,4-dimethyl-2-oxo-3-[(S)-1-((R)-1-phenyl-ethy...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179445((S)-4,4-dimethyl-2-oxo-1-((4-(trifluoromethyl)phen...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179440((S)-1-(benzo[b]thiophene-2-carbonyl)-4,4-dimethyl-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165424((S)-4,4-dimethyl-2-oxo-tetrahydrofuran-3-yl (S)-1,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179442((S)-4,4-dimethyl-2-oxo-1-(2-phenylacetyl)pyrrolidi...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179453((S)-1-(benzylcarbamoyl)-4,4-dimethyl-2-oxopyrrolid...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179441((S)-4,4-dimethyl-2-oxo-1-(phenylcarbamoyl)pyrrolid...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179435((S)-4,4-dimethyl-2-oxo-3-[(S)-1-((R)-1-phenyl-ethy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179433((S)-4,4-dimethyl-2-oxo-1-(phenethylcarbamoyl)pyrro...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179456(CHEMBL380300 | [(S)-1-((R)-1-phenyl-ethylaminooxal...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179434((S)-4,4-dimethyl-2-oxo-1-(phenylsulfonyl)pyrrolidi...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179444((S)-1-(isoxazole-5-carbonyl)-4,4-dimethyl-2-oxopyr...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179457((S)-4,4-dimethyl-1-nicotinoyl-2-oxopyrrolidin-3-yl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179432((S)-1-((3,5-dimethylisoxazol-4-yl)carbamoyl)-4,4-d...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179450((S)-4,4-dimethyl-1-(morpholine-4-carbonyl)-2-oxopy...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179452((S)-1-(benzylsulfonyl)-4,4-dimethyl-2-oxopyrrolidi...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179455((S)-1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-yl (S)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179447((S)-benzyl 3-(((S)-1,2-dioxo-1-((R)-1-phenylethyla...)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179443((S)-4,4-dimethyl-2-oxo-1-(4-phenylbutanoyl)pyrroli...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179449((S)-phenyl 3-(((S)-1,2-dioxo-1-((R)-1-phenylethyla...)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179451((S)-phenethyl 3-(((S)-1,2-dioxo-1-((R)-1-phenyleth...)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179448((S)-naphthalen-2-yl 3-(((S)-1,2-dioxo-1-((R)-1-phe...)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50179436((S)-1-benzoyl-4,4-dimethyl-2-oxopyrrolidin-3-yl (S...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed