Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50037678
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179532(1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179555((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179548(1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179543((4-{(S)-2-[(S)-2-(biphenyl-3-ylamino)-4-methyl-pen...)
Affinity DataIC50:  4.5nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179547(CHEMBL557986 | [4-((S)-2-{[1-(biphenyl-3-ylamino)-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179539(CHEMBL383551 | [4-((S)-2-{[1-(biphenyl-3-ylamino)-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179542(1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179558((4-{(S)-2-[(S)-2-(biphenyl-3-ylamino)-4-methyl-pen...)
Affinity DataIC50:  6.40nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179551(1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179559((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179538((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179549((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179556((S)-2-(3-cyclohexylphenylamino)-N-(2-(4-methoxyphe...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179560(CHEMBL383473 | N-(2-(4-methoxyphenylamino)ethyl)-4...)
Affinity DataIC50:  69nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179550(1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  82nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179534(1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  83nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179537(2-(biphenyl-3-yloxy)-4-methyl-pentanoic acid [2-(4...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50113676((S)-benzyl 1-(2-(4-methoxyphenylamino)ethylamino)-...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179553(1-(4-cyclohexylphenoxy)-N-(2-(4-methoxyphenylamino...)
Affinity DataIC50:  99nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179540(1-(biphenyl-4-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179561(2-(biphenyl-4-yloxy)-4-methyl-pentanoic acid [2-(4...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179557(1-(4-ethylphenoxy)-N-(2-(4-methoxyphenylamino)ethy...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179546(1-(biphenyl-4-yloxy)-cyclohexanecarboxylic acid [2...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179536(1-(4-isopropylphenoxy)-N-(2-(4-methoxyphenylamino)...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179541(1-(biphenyl-3-yloxy)-cyclohexanecarboxylic acid [2...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179545(CHEMBL203176 | N-(2-(4-methoxyphenylamino)ethyl)-4...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179533(2-(biphenyl-2-yloxy)-4-methyl-pentanoic acid [2-(4...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179554(CHEMBL203576 | N-(2-(4-methoxyphenylamino)ethyl)-1...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179535(CHEMBL205923 | N-(2-(4-methoxyphenylamino)ethyl)-4...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179552(CHEMBL203450 | N-(2-(4-methoxyphenylamino)ethyl)-1...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50179544(1-(biphenyl-2-ylamino)-cyclohexanecarboxylic acid ...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed