Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50017264
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179860BDBM50179860(N-cyclopentyl-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  8nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19993BDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  10nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179858BDBM50179858(1,1,1,3,3,3-hexafluoro-2-(1-(phenylsulfonyl)-2,3,4...)
Affinity DataEC50:  10nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179864BDBM50179864(3-cyano-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop...)
Affinity DataEC50:  20nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179872BDBM50179872(biphenyl-3-sulfonic acid methyl-[4-(2,2,2-trifluor...)
Affinity DataEC50:  30nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179877BDBM50179877(1,1,1,3,3,3-hexafluoro-2-(1-(phenylsulfonyl)-1,2,3...)
Affinity DataEC50:  30nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179866BDBM50179866(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataEC50:  40nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179880BDBM50179880(1,1,1,3,3,3-hexafluoro-2-(1-(phenylsulfonyl)indoli...)
Affinity DataEC50:  50nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179870BDBM50179870(N1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl...)
Affinity DataEC50:  80nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179876BDBM50179876(1,1,1,3,3,3-hexafluoro-2-(4-(phenylsulfonyl)-3,4-d...)
Affinity DataEC50:  100nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179859BDBM50179859(isobutyl 4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan...)
Affinity DataEC50:  100nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179863BDBM50179863(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataEC50:  100nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179875BDBM50179875(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N-...)
Affinity DataEC50:  100nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179879BDBM50179879(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N-...)
Affinity DataEC50:  200nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179869BDBM50179869(N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  200nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179874BDBM50179874(N-(2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypro...)
Affinity DataEC50:  200nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20164BDBM20164(CHEMBL434302 | (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)...)
Affinity DataEC50:  500nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179878BDBM50179878(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataEC50:  600nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179865BDBM50179865(2-cyano-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop...)
Affinity DataEC50:  700nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179873BDBM50179873(N-(3-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataEC50:  1.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179862BDBM50179862(N-(4-(1,1,1,3,3,3-hexafluoro-2-methoxypropan-2-yl)...)
Affinity DataEC50:  1.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179857BDBM50179857(4-cyano-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop...)
Affinity DataEC50:  2.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179861BDBM50179861(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179867BDBM50179867(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...)
Affinity DataEC50:  4.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179868BDBM50179868(N-methyl-N-(4-(2,2,2-trifluoro-1-hydroxyethyl)phen...)
Affinity DataEC50: >5.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179856BDBM50179856(N-(3-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypro...)
Affinity DataEC50: >5.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50179871BDBM50179871(N-methyl-N-(4-(1,1,1-trifluoro-2-hydroxypropan-2-y...)
Affinity DataEC50:  5.00E+3nMAssay Description:Activity against LXR alpha transiently transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed