Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50017367
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181089(UCB-101333-3 | 6-(azepan-1-yl)-N,2-dicyclopropyl-5...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181100(6-(3-aza-bicyclo[3.2.1]octan-3-yl)-N,2-dicycloprop...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181094(6-(azepan-1-yl)-N-cyclobutyl-2-cyclopropyl-5-methy...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181118((+,-)-6-(azepan-1-yl)-2-cyclopropyl-5-methyl-N-(2-...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181105(4-(azepan-1-yl)-2-cyclopropyl-6,7,8,9-tetrahydro-5...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181114(6-(azepan-1-yl)-2-cyclopropyl-5-methyl-N-(1-methyl...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181134(N,2-dicyclopropyl-5-methyl-6-(piperidin-1-yl)pyrim...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181107(N,2-dicyclopropyl-5-methyl-6-(4-methylpiperidin-1-...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181096(6-(azocan-1-yl)-N,2-dicyclopropyl-5-methylpyrimidi...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181128(6-(azepan-1-yl)-N-cyclopropyl-2-isopropyl-5-methyl...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181121(N,2-dicyclopropyl-6-(4,4-dimethylpiperidin-1-yl)-5...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181111(N,2-dicyclopropyl-6-(5,6-dihydropyridin-1(2H)-yl)-...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181108((-)-6-(azepan-1-yl)-N-cyclopropyl-5-methyl-2-(2-me...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181106(6-(azepan-1-yl)-2-cyclobutyl-N-cyclopropyl-5-methy...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181103(4-(azepan-1-yl)-2-cyclopropyl-5,6,7,8-tetrahydropy...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181109(N,2-dicyclopropyl-6-(4-ethylpiperidin-1-yl)-5-meth...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181101(N,2-dicyclopropyl-6-(4,4-difluoropiperidin-1-yl)-5...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181123(6-(azepan-1-yl)-N,2-dicyclopropylpyrimidin-4-amine...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181092(N4-(2,6-difluorobenzyl)-N6,2-dicyclopropyl-5-methy...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181116(N4,2-dicyclopropyl-5-methyl-N6-(2-(thiophen-2-yl)e...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181132(cyclopropyl-(2-cyclopropyl-5-methyl-6-thiomorpholi...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181088(6-(azepan-1-yl)-N4,2-dicyclopropylpyrimidine-4,5-d...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181127(6-(azepan-1-yl)-2-cyclopentyl-N-cyclopropyl-5-meth...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181120(N,2-dicyclopropyl-5-methyl-6-(4-methylenepiperidin...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181133(N,2-dicyclopropyl-5-methyl-6-(4-(trifluoromethyl)p...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181131(N,2-dicyclopropyl-5-methyl-6-(pyrrolidin-1-yl)pyri...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181102(N,2-dicyclopropyl-5-ethyl-6-thiomorpholinopyrimidi...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181112(N4,2-dicyclopropyl-5-methyl-N6-(thiophen-2-ylmethy...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181115(6-(azepan-1-yl)-N-cyclopropyl-2-(cyclopropylmethyl...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181122([6-(8-aza-spiro[4.5]dec-8-yl)-2-cyclopropyl-5-meth...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181098(N4-benzyl-N6,2-dicyclopropyl-5-methylpyrimidine-4,...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181129(6-(azepan-1-yl)-N,2-dicyclopropyl-5-fluoropyrimidi...)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181104(N4-benzyl-N6,2-dicyclopropyl-N4,5-dimethylpyrimidi...)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181125(N,2-dicyclopropyl-6-(3,4-dihydroisoquinolin-2(1H)-...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181119(N4-cyclohexyl-N6,2-dicyclopropyl-5-methylpyrimidin...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181097(6-(azepan-1-yl)-5-bromo-N,2-dicyclopropylpyrimidin...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181095(N,2-dicyclopropyl-5-methoxy-6-thiomorpholinopyrimi...)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181110(N4-cycloheptyl-N6,2-dicyclopropyl-5-methylpyrimidi...)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181093((+)-6-(azepan-1-yl)-N-cyclopropyl-2-(2-methylcyclo...)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181091(1-(2-cyclopropyl-6-(cyclopropylamino)-5-methylpyri...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181090((1-(2-cyclopropyl-6-(cyclopropylamino)-5-methylpyr...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181099(6-(azepan-1-yl)-2-benzyl-N-cyclopropyl-5-methylpyr...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181117(6-(4-benzylpiperidin-1-yl)-N,2-dicyclopropyl-5-met...)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181124(6-(azepan-1-yl)-N,2-dicyclopropyl-5-nitropyrimidin...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50181126(1-(2-cyclopropyl-6-(cyclopropylamino)-5-methylpyri...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]methylscopolamine from recombinant human muscarinic M3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed