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Found 12 Enz. Inhib. hit(s) with all data for entry = 50017375
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM34064(2-arylbenzimidazole | CHEMBL179583)
Affinity DataIC50:  16nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50163284(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...)
Affinity DataIC50:  55nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181269(2-(4-(4-chlorophenoxy)phenyl)-1H-imidazo[4,5-b]pyr...)
Affinity DataIC50:  77nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181265(2-(4-(4-chlorophenoxy)phenyl)-1H-benzo[d]imidazole...)
Affinity DataIC50:  133nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50163289(2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...)
Affinity DataIC50:  640nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181262(3-methyl-2-(4-phenoxyphenyl)-3H-benzo[d]imidazole-...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181263(2-(4-(4-chlorophenoxy)phenyl)-3H-imidazo[4,5-b]pyr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181268(2-(4-(4-chlorophenoxy)phenyl)-1H-indole-6-carboxyl...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181267(2-(4-phenoxyphenyl)benzo[d]oxazole-5-carboxamide |...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181270(1-methyl-2-(4-phenoxyphenyl)-1H-benzo[d]imidazole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181264(2-(4-phenoxyphenyl)benzo[d]oxazole-6-carboxamide |...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50181266(2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-6-car...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed