Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with all data for entry = 50037655
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  0.510nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184L expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50:  0.610nMAssay Description:Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I129A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I291A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50:  0.710nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50:  0.820nMAssay Description:Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human wild type MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  0.920nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181498((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...)
Affinity DataEC50:  1.02nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at the mutant MC4R I129A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I125A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I125A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human wild type MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184L expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181499(c[Ser-Tyr-Thr-His-Dphe-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I291A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I291A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181498((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human wild type MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataEC50:  8.5nMAssay Description:Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50151511(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181497(c[Thr-Tyr-Thr-His-DNaf-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121900(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50181499(c[Ser-Tyr-Thr-His-Dphe-Arg-Trp-Thr-Ile-Pro] | CHEM...)
Affinity DataEC50:  9.5nMAssay Description:Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
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