Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50017486
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157734BDBM50157734(2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyr...)
Affinity DataIC50: 570nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182775BDBM50182775(3-allyl-5,8-dichloro-1,2,3,4-tetrahydrocyclopenta[...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182777BDBM50182777(3-butyl-8-cyano-7-fluoro-5-methyl-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182768BDBM50182768(8-cyano-7-fluoro-5-methyl-3-propyl-1,2,3,4-tetrahy...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182788BDBM50182788(3-butyl-5,8-dichloro-1,2,3,4-tetrahydrocyclopenta[...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182786BDBM50182786(2-(5-cyano-8-fluoro-1-propyl-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182765BDBM50182765(2-(5-cyano-8-methyl-1-propyl-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182769BDBM50182769(2-(5,8-dicyano-1-propyl-2,3,4,9-tetrahydro-1H-carb...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182785BDBM50182785(5,8-dichloro-1-propyl-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182789BDBM50182789(3-butyl-8-cyano-5-methyl-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182783BDBM50182783(8-cyano-5-methyl-3-propyl-1,2,3,4-tetrahydrocyclop...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182774BDBM50182774(3-butyl-8-cyano-5-fluoro-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182776BDBM50182776(8-chloro-1-propyl-5-(trifluoromethyl)-2,3,4,9-tetr...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182773BDBM50182773(3-allyl-8-cyano-7-fluoro-5-methyl-1,2,3,4-tetrahyd...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182778BDBM50182778(8-cyano-5-fluoro-3-propyl-1,2,3,4-tetrahydrocyclop...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182781BDBM50182781(5-cyano-8-fluoro-1-propyl-2,3,4,9-tetrahydro-1H-ca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182780BDBM50182780(3-allyl-8-cyano-5-methyl-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182767BDBM50182767(3-allyl-8-cyano-5-fluoro-1,2,3,4-tetrahydrocyclope...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182770BDBM50182770(5-cyano-8-methyl-1-propyl-2,3,4,9-tetrahydro-1H-ca...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182771BDBM50182771(5,8-dichloro-3-propyl-1,2,3,4-tetrahydrocyclopenta...)
Affinity DataIC50: 2.70E+4nMAssay Description:Antiviral activity against Hepatitis C virus replicon in Huh7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182771BDBM50182771(5,8-dichloro-3-propyl-1,2,3,4-tetrahydrocyclopenta...)
Affinity DataIC50: 2.70E+4nMAssay Description:Antiviral activity against Hepatitis C virus replicon in Huh7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182779BDBM50182779(2-(5,7-difluoro-1-propyl-2,3,4,9-tetrahydro-1H-car...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182787BDBM50182787(2-(5,8-difluoro-1-propyl-2,3,4,9-tetrahydro-1H-car...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182784BDBM50182784(2-(1-propyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)ac...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182766BDBM50182766(2-(7,8-difluoro-1-propyl-2,3,4,9-tetrahydro-1H-car...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182782BDBM50182782(2-(6-bromo-8-chloro-1-propyl-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182772BDBM50182772(2-(8-carbamoyl-5-cyano-1-propyl-2,3,4,9-tetrahydro...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182790BDBM50182790(2-(6-chloro-1-propyl-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of HCV 1b BK NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed