Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50037697
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182194(CHEMBL206418 | {(R)-2-[(S)-2-(4-carbamimidoyl-benz...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183870(((R)-2-{(S)-2-[(4-carbamimidoyl-3-chloro-thiophen-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183879(((R)-2-{(S)-2-[(4-carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183872(((R)-2-{(S)-2-[(5-carbamimidoyl-4-chloro-thiophen-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50129034(((R)-2-{(S)-2-[(5-Carbamimidoyl-1H-pyrrol-2-ylmeth...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183880(((R)-2-{(S)-2-[(5-carbamimidoyl-thiophen-3-ylmethy...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183878(((R)-2-{(S)-2-[(4-carbamimidoyl-3-methyl-thiophen-...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50129033(((R)-2-{(S)-2-[(5-Carbamimidoyl-1-methyl-1H-pyrrol...)
Affinity DataIC50:  11nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183875(((R)-2-{(S)-2-[(4-carbamimidoyl-oxazol-2-ylmethyl)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183887(((R)-2-{(S)-2-[(3-carbamimidoyl-isoxazol-5-ylmethy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183888(((R)-2-{(S)-2-[(2-carbamimidoyl-thiazol-4-ylmethyl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183866(((R)-2-{(S)-2-[(5-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183876(((R)-2-{(S)-2-[(5-carbamimidoyl-pyridin-2-ylmethyl...)
Affinity DataIC50:  51nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183869(((R)-2-{(S)-2-[(5-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  51nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183890(((R)-2-{(S)-2-[(5-amino-4-carbamimidoyl-thiophen-2...)
Affinity DataIC50:  57nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  70nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  125nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  173nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  201nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183886(((R)-2-{(S)-2-[(5-carbamimidoyl-2-methyl-2H-[1,2,4...)
Affinity DataIC50:  232nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  251nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  328nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  540nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183884(((R)-2-{(S)-2-[(5-carbamimidoyl-[1,3,4]thiadiazol-...)
Affinity DataIC50:  566nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50:  687nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  995nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183873(((R)-2-{(S)-2-[(5-carbamimidoyl-1-methyl-1H-pyrazo...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183874(((R)-2-{(S)-2-[(5-carbamimidoyl-3,4-dimethyl-thiop...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183889(((R)-2-{(S)-2-[(3-carbamimidoyl-[1,2,4]oxadiazol-5...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183881(((R)-2-{(S)-2-[(3-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183871(((R)-2-{(S)-2-[(4-carbamimidoyl-5-methyl-thiazol-2...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  3.27E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed