Compile Data Set for Download or QSAR
maximum 50k data
Found 61 Enz. Inhib. hit(s) with all data for entry = 50017725
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185781(4-(2,4-difluorophenethyl)-1-(2-(naphthalen-1-yl)ph...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185778(8-(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfo...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185784((4-(2,4-difluorophenethyl)piperidin-1-yl)(quinolin...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185772(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185782(4-(2,4-difluorophenethyl)-1-(2-chlorophenylsulfony...)
Affinity DataKi:  6.10nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185783(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl...)
Affinity DataKi:  8.10nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185777(4-(2,4-difluorophenethyl)-1-(2-fluorophenylsulfony...)
Affinity DataKi:  9.90nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185773(4-(2,4-difluorophenethyl)-1-(3-fluorophenylsulfony...)
Affinity DataKi:  14nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  22nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185785(4-(2,4-difluorophenethyl)-4-fluoro-1-(4-fluorophen...)
Affinity DataKi:  24nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185784((4-(2,4-difluorophenethyl)piperidin-1-yl)(quinolin...)
Affinity DataKi:  28nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185774(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  52nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185783(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl...)
Affinity DataKi:  70nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  92nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185781(4-(2,4-difluorophenethyl)-1-(2-(naphthalen-1-yl)ph...)
Affinity DataKi:  96nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  110nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185778(8-(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfo...)
Affinity DataKi:  184nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  190nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185777(4-(2,4-difluorophenethyl)-1-(2-fluorophenylsulfony...)
Affinity DataKi:  239nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185782(4-(2,4-difluorophenethyl)-1-(2-chlorophenylsulfony...)
Affinity DataKi:  404nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  449nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)
Affinity DataKi:  557nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  710nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185785(4-(2,4-difluorophenethyl)-4-fluoro-1-(4-fluorophen...)
Affinity DataKi:  806nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185773(4-(2,4-difluorophenethyl)-1-(3-fluorophenylsulfony...)
Affinity DataKi:  997nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185778(8-(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfo...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185773(4-(2,4-difluorophenethyl)-1-(3-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185772(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185781(4-(2,4-difluorophenethyl)-1-(2-(naphthalen-1-yl)ph...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185782(4-(2,4-difluorophenethyl)-1-(2-chlorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185777(4-(2,4-difluorophenethyl)-1-(2-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185774(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185785(4-(2,4-difluorophenethyl)-4-fluoro-1-(4-fluorophen...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185784((4-(2,4-difluorophenethyl)piperidin-1-yl)(quinolin...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50108699(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185783(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185779(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)...)
Affinity DataKi:  1.27E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185774(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi:  2.03E+3nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185772(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  3.79E+3nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185776(4-(2,4-difluorophenethyl)-1-(4-fluorophenylsulfony...)
Affinity DataKi: >4.00E+3nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185772(1-(2,4-difluorophenethyl)-4-(4-fluorophenylsulfony...)
Affinity DataKi:  4.87E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185782(4-(2,4-difluorophenethyl)-1-(2-chlorophenylsulfony...)
Affinity DataKi: >9.00E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185777(4-(2,4-difluorophenethyl)-1-(2-fluorophenylsulfony...)
Affinity DataKi: >9.00E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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