Compile Data Set for Download or QSAR
Report error Found 108 Enz. Inhib. hit(s) with all data for entry = 50017874
LigandChemical structure of BindingDB Monomer ID 50187780BDBM50187780(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N4-hyd...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187792BDBM50187792(1-(benzylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187786BDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 30144BDBM30144(CHEMBL212481 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187779BDBM50187779(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N1,N1-...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187783BDBM50187783(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 30136BDBM30136(CHEMBL385821 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 23500BDBM23500(CHEMBL209970 | 4-({[4-(but-2-yn-1-yloxy)benzene]su...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187789BDBM50187789(1-(2-aminobenzoyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187790BDBM50187790(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187784BDBM50187784(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187794BDBM50187794(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187795BDBM50187795(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 30140BDBM30140(CHEMBL380049 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187781BDBM50187781(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(but...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187796BDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187788BDBM50187788(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187799BDBM50187799(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyc...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187797BDBM50187797(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187793BDBM50187793(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187792BDBM50187792(1-(benzylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187782BDBM50187782(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187798BDBM50187798(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N4-hyd...)
Affinity DataIC50: 4nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187787BDBM50187787(1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187785BDBM50187785(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50187791BDBM50187791(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 6nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187786BDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187792BDBM50187792(1-(benzylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187791BDBM50187791(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187784BDBM50187784(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 14nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187784BDBM50187784(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187789BDBM50187789(1-(2-aminobenzoyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 16nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187792BDBM50187792(1-(benzylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187786BDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187781BDBM50187781(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(but...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187795BDBM50187795(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187791BDBM50187791(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187796BDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187789BDBM50187789(1-(2-aminobenzoyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 39nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187781BDBM50187781(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(but...)
Affinity DataIC50: 44nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187795BDBM50187795(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 46nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187796BDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 49nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187788BDBM50187788(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 54nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187788BDBM50187788(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 54nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30144BDBM30144(CHEMBL212481 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50: 62nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187792BDBM50187792(1-(benzylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulf...)
Affinity DataIC50: 65nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187784BDBM50187784(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 68nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30144BDBM30144(CHEMBL212481 | beta-sulfone piperidine hydroxamate...)
Affinity DataIC50: 69nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187782BDBM50187782(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: 69nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50187779BDBM50187779(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N1,N1-...)
Affinity DataIC50: 74nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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