Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50000593
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007558(CHEMBL292163 | 6-[2-(4-Naphthalen-1-yl-piperazin-1...)
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007563(CHEMBL56536 | 1-Ethyl-5-[2-(4-naphthalen-1-yl-pipe...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 3.10nMAssay Description:Compound was evaluated In vitro for its activity by binding to Dopamine receptor D2 in the rat brain using [3H]NPA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 4.87nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007556(CHEMBL55362 | 6-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 6.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007557(CHEMBL294702 | 3,3-Dimethyl-5-[2-(4-naphthalen-1-y...)
Affinity DataIC50: 6.90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007562(CHEMBL300849 | 4-{4-[2-(4-Naphthalen-1-yl-piperazi...)
Affinity DataIC50: 11nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007559(CHEMBL54786 | 5-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 38nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007556(CHEMBL55362 | 6-[2-(4-Naphthalen-1-yl-piperazin-1-...)
Affinity DataIC50: 44nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007562(CHEMBL300849 | 4-{4-[2-(4-Naphthalen-1-yl-piperazi...)
Affinity DataIC50: 72nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007565(CHEMBL55055 | 4-{4-[2-(4-Naphthalen-1-yl-piperazin...)
Affinity DataIC50: 80nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007563(CHEMBL56536 | 1-Ethyl-5-[2-(4-naphthalen-1-yl-pipe...)
Affinity DataIC50: 81.2nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007560(CHEMBL53565 | 1-Naphthalen-1-yl-4-[2-(4-[1,2,3]thi...)
Affinity DataIC50: 83nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007557(CHEMBL294702 | 3,3-Dimethyl-5-[2-(4-naphthalen-1-y...)
Affinity DataIC50: 86nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007566(CHEMBL54910 | 1-{2-[4-(2-Methyl-thiazol-4-yl)-phen...)
Affinity DataIC50: 108nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007558(CHEMBL292163 | 6-[2-(4-Naphthalen-1-yl-piperazin-1...)
Affinity DataIC50: 112nMAssay Description:Compound was evaluated In vitro for its activity by binding to Dopamine receptor D2 in the rat brain using [3H]NPA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007564(CHEMBL55806 | Methyl-(4-{4-[2-(4-naphthalen-1-yl-p...)
Affinity DataIC50: 155nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007561(CHEMBL292201 | 5-Methyl-4-{4-[2-(4-naphthalen-1-yl...)
Affinity DataIC50: 159nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 172nMAssay Description:Compound was evaluated In vitro for its activity by binding to Dopamine receptor D2 in the rat brain using [3H]NPA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 600nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed