Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50037754
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135703BDBM50135703(CHEMBL345732 | CHEMBL99367 | Trimethyl-[2-(pyridin...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity at alpha4beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135703BDBM50135703(CHEMBL345732 | CHEMBL99367 | Trimethyl-[2-(pyridin...)
Affinity DataKi:  280nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  750nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188956BDBM50188956(N,N,N-trimethyl-2-phenoxyethanaminium | CHEMBL2098...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188954BDBM50188954(N,N,N-trimethyl-2-(6-styrylpyridin-3-yloxy)ethanam...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188952BDBM50188952(N,N,N-trimethyl-2-(4-styrylphenoxy)ethanaminium | ...)
Affinity DataKi:  2.17E+3nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188948BDBM50188948(N,N,N-trimethyl-2-(6-phenethylpyridin-3-yloxy)etha...)
Affinity DataKi:  4.32E+3nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188957BDBM50188957(N,N,N-trimethyl-2-(4-phenethylphenoxy)ethanaminium...)
Affinity DataKi:  7.50E+3nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188964BDBM50188964(N,N-dimethyl-2-(4-phenethylphenoxy)ethanaminium)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119573BDBM50119573(N,N-dimethyl-3-(pyridin-3-yl)propan-1-amine | Dime...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188963BDBM50188963(Methyl-((E)-3-pyridin-3-yl-allyl)-amine | N-methyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188962BDBM50188962(N,N-dimethyl-2-phenoxyethanaminium)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119558BDBM50119558(xDimethyl-(3-pyridin-3-yl-propyl)-amineDimethyl-(3...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188960BDBM50188960(N,N-dimethyl-2-(6-phenethylpyridin-3-yloxy)ethanam...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115811BDBM50115811(Ethyl-methyl-[2-(pyridin-3-yloxy)-ethyl]-amine | N...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188953BDBM50188953(N,N,N-trimethyl-3-(pyridin-3-yloxy)propan-1-aminiu...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188951BDBM50188951(N-methyl-3-(pyridin-3-yl)prop-2-en-1-amine | CHEMB...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188950BDBM50188950(N-methyl-3-(pyridin-3-yl)propan-1-amine | CHEMBL21...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115808BDBM50115808(Dimethyl-[2-(pyridin-3-yloxy)-ethyl]-amine | N,N-d...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120586BDBM50120586(Methyl-[2-(pyridin-3-yloxy)-ethyl]-amine | N-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188958BDBM50188958(N,N-dimethyl-2-(6-styrylpyridin-3-yloxy)ethanamini...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168255BDBM50168255((+/-)6-(2-Phenylethyl)nicotine | 5-(1-Methyl-pyrro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188955BDBM50188955(N,N-dimethyl-2-(4-styrylphenoxy)ethanaminium)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed