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Found
15
Enz. Inhib. hit(s) with all data for entry = 50018024
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50190001
(N-(5-chloro-2-fluorophenyl)-7-methoxy-6-(1-(methyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50190000
(N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50190002
(N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(1-(methyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189993
(2-(4-(4-(3-chloro-2-fluorophenylamino)-7-methoxyqu...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189995
(N-(3-chloro-2-fluorophenyl)-7-methoxy-6-((1-methyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189991
(N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(1-(2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189990
(N-(3-chloro-4-fluorophenyl)-7-methoxy-6-((1-methyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189998
(N-(5-chloro-2-fluorophenyl)-7-methoxy-6-((1-methyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50190003
(2-(4-(4-(5-chloro-2-fluorophenylamino)-7-methoxyqu...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189994
(N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189992
(N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(3-morphol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM5447
(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189997
(N-(5-chloro-2-fluorophenyl)-7-methoxy-6-(3-morphol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189999
(N-(5-chloro-2-fluorophenyl)-7-methoxy-6-(1-methylp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 106nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Epidermal growth factor receptor
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50189996
(N-(5-chloro-2-fluorophenyl)-7-methoxy-6-(1-(2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 114nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
11/10/2009
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL