Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 1992
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15916BDBM15916(4-(5-{[(4-Amino-5-cyano-6-ethoxy-pyridine-2-carbon...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15916BDBM15916(4-(5-{[(4-Amino-5-cyano-6-ethoxy-pyridine-2-carbon...)
Affinity DataIC50: 11nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15914BDBM15914(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15913BDBM15913(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 19nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15918BDBM15918(4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphe...)
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15915BDBM15915(4-amino-5-cyano-6-ethoxy-N-(pyridin-3-ylmethyl)pyr...)
Affinity DataIC50: 26nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15915BDBM15915(4-amino-5-cyano-6-ethoxy-N-(pyridin-3-ylmethyl)pyr...)
Affinity DataIC50: 41nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15908BDBM15908(N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-di...)
Affinity DataIC50: 45nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15914BDBM15914(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 53nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15919BDBM15919(4-Amino-5-chloro-6-isopropoxy-pyridine-2-carboxyli...)
Affinity DataIC50: 68nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15909BDBM15909(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 71nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15918BDBM15918(4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphe...)
Affinity DataIC50: 74nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15919BDBM15919(4-Amino-5-chloro-6-isopropoxy-pyridine-2-carboxyli...)
Affinity DataIC50: 75nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15909BDBM15909(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 120nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15913BDBM15913(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 120nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15912BDBM15912(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 190nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15922BDBM15922(5-cyano-N-[(2,5-dimethoxyphenyl)methyl]-6-ethoxypy...)
Affinity DataIC50: 230nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15912BDBM15912(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 270nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15921BDBM15921(5-cyano-6-ethoxy-N-[(4-methanesulfonylphenyl)methy...)
Affinity DataIC50: 390nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15911BDBM15911(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 610nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15907BDBM15907(Aminopyridine-Based Inhibitor 6a | N-(4-Amino-5-cy...)
Affinity DataIC50: 840nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15911BDBM15911(4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic aci...)
Affinity DataIC50: 1.20E+3nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15920BDBM15920(4-amino-6-chloro-5-cyano-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 1.50E+3nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15920BDBM15920(4-amino-6-chloro-5-cyano-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 4.40E+3nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15917BDBM15917(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 6.40E+3nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15910BDBM15910(4-Amino-6-(2,5-dimethoxy-benzylamino)-2-ethoxy-nic...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 15917BDBM15917(4-amino-5-cyano-6-ethoxy-N-[(4-methanesulfonylphen...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed