Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50037718
LigandPNGBDBM50191431(5-bromoindirubin-3'-oxime | CHEMBL379494)
Affinity DataIC50: 28nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM7401(6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...)
Affinity DataIC50: 83nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50132003((Z)-1H,1''H-[2,3'']Biindolylidene-3,2''-dione 3-ox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191421(3-(3-(methoxyimino)indolin-2-ylidene)indolin-2-one...)
Affinity DataIC50: 400nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191448((2'Z,3'E)-7-fluoroindirubin-3'-oxime | CHEMBL21217...)
Affinity DataIC50: 510nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191394(2,3'-biindole-2',3(1H,1'H)-dione 3-(O-acetyloxime)...)
Affinity DataIC50: 700nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: 5.20E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191436((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: 5.40E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191418((2'Z,3'E)-7-chloroindirubin-3'-oxime | CHEMBL21365...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191429((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-imidazol-1-yle...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191403((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dieth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191437((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-morpholin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191400((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-bromo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191422((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191428((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-morph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191435((2'Z,3'E)-1-Methyl-7-bromoindirubin-3'-[O-(2-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191447((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-diethylaminoet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191426(CHEMBL213401 | CHEMBL211093 | (2'Z,3'E)-7-bromoind...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191436((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191430((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-morph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191446((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-morpholin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191411((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191426(CHEMBL213401 | CHEMBL211093 | (2'Z,3'E)-7-bromoind...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191404((2'Z, 3'E)-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191415((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191444((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(N,Ndiet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191429((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-imidazol-1-yle...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191399((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dieth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50349806(INDIRUBIN)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191402((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191395((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191396((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50: 1.30E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191395((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrro...)
Affinity DataIC50: 1.88E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191405((2'Z,3'E)-7-bromoindirubin-3'-oxime | CHEMBL373834)
Affinity DataIC50: 2.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191422((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimet...)
Affinity DataIC50: 2.40E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191438((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-bromoethyl)oxi...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191396((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191415((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-y...)
Affinity DataIC50: 3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50191411((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191405((2'Z,3'E)-7-bromoindirubin-3'-oxime | CHEMBL373834)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191398((2'Z,3'E)-7-iodoindirubin-3'-oxime | CHEMBL209648)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191434((2'Z,3'E)-7-chloro-1-methylindirubin-3'-oxime | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191427((2'Z,3'E)-7-fluoro-1-methylindirubin-3'-acetoxime ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191417((2'Z,3'E)-7-iodoindirubin-3'-methoxime | CHEMBL213...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191409((2'Z,3'E)-7-chloro-1-methylindirubin-3'-acetoxime ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191410(3-(3-(hydroxyimino)indolin-2-ylidene)-1-methylindo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50191392((2'Z,3'E)-7-bromo-1-methylindirubin-3'-acetoxime |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
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