Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50037765
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189360BDBM50189360((1S,10S)-9-[(Isoquinoline-1-carbonyl)-amino]-6,10-...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191907BDBM50191907(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189360BDBM50189360((1S,10S)-9-[(Isoquinoline-1-carbonyl)-amino]-6,10-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191905BDBM50191905(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191909BDBM50191909(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191902BDBM50191902(isoquinoline-1-carboxylic acid {(R)-4-[((S)-2-hydr...)
Affinity DataIC50: 130nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191901BDBM50191901(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191906BDBM50191906(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191908BDBM50191908(benzo[b]thiophene-2-carboxylic acid {(R)-4-[((S)-2...)
Affinity DataIC50: 320nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191904BDBM50191904(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189360BDBM50189360((1S,10S)-9-[(Isoquinoline-1-carbonyl)-amino]-6,10-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191899BDBM50191899(N-{(R)-4-[((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191902BDBM50191902(isoquinoline-1-carboxylic acid {(R)-4-[((S)-2-hydr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191904BDBM50191904(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191905BDBM50191905(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191908BDBM50191908(benzo[b]thiophene-2-carboxylic acid {(R)-4-[((S)-2...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191907BDBM50191907(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191909BDBM50191909(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191909BDBM50191909(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191902BDBM50191902(isoquinoline-1-carboxylic acid {(R)-4-[((S)-2-hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191901BDBM50191901(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191905BDBM50191905(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191908BDBM50191908(benzo[b]thiophene-2-carboxylic acid {(R)-4-[((S)-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191907BDBM50191907(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191906BDBM50191906(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191906BDBM50191906(N-((R)-4-(2-((S)-2-hydroxy-5-oxo-tetrahydrofuran-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191899BDBM50191899(N-{(R)-4-[((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191899BDBM50191899(N-{(R)-4-[((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191904BDBM50191904(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191901BDBM50191901(N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-tetrahydrofuran-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed