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Found 21 Enz. Inhib. hit(s) with all data for entry = 1401
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11292(1,5-dichloro-2-{[2,6-dinitro-4-(trifluoromethyl)be...)
Affinity DataIC50:  300nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11293(4-({4-[(2,3,3-trichloroprop-2-enoyl)oxy]benzene}su...)
Affinity DataIC50:  900nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11304(Compound 2 analog 15 | MurB inhibitor (compound 16...)
Affinity DataIC50:  3.00E+3nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11305(5-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-N...)
Affinity DataIC50:  5.00E+3nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11294(5-[(4-chlorobenzene)sulfonyl]pyrimidine-2,4-diamin...)
Affinity DataIC50:  6.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11306(Compound 2 analog 17 | N-[3-(5-tert-butyl-2-methyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11295(1-[(4-chlorobenzene)sulfonyl]-2-nitro-4-(trifluoro...)
Affinity DataIC50:  1.20E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11297(4,6-dimethyl-2-[(4-methylbenzene)sulfonyl]-5-nitro...)
Affinity DataIC50:  1.30E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11296(2-(benzenesulfonyl)-4,6-dimethyl-5-nitropyridine-3...)
Affinity DataIC50:  1.30E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11298(2-[(4-chlorobenzene)sulfonyl]-5-nitro-1-oxidopyrid...)
Affinity DataIC50:  1.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11307(Compound 2 analog 18 | N-{4-[(4-chlorobenzene)sulf...)
Affinity DataIC50:  1.50E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11301(2-[(2-acetylbenzene)sulfonyl]benzoic acid | Compou...)
Affinity DataIC50:  1.60E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11300(4-[(3,5-dibromo-4-hydroxybenzene)sulfonyl]benzoic ...)
Affinity DataIC50:  1.60E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11299(Compound 1 analog 10 | ethyl (2E)-2-cyano-3-({4-[(...)
Affinity DataIC50:  1.60E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11308(3-[(furan-2-ylmethyl)amino]-6,6-dimethyl-4-oxo-4,5...)
Affinity DataIC50:  1.60E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11309(1-(1,3-dimethyl-4-nitro-1H-pyrazol-5-yl)-3-(methyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11310(4-(5-chlorothiophen-2-yl)-2-[(thiophene-2-sulfonyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11311(1,3-dimethyl-4-nitro-N-{[5-(thiophen-2-yl)thiophen...)
Affinity DataIC50:  2.00E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11302(1-nitro-4-[(4-nitrobenzene)sulfonyl]benzene | Comp...)
Affinity DataIC50:  2.50E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11303(1,3-diethyl 2-[({4-[(4-{[3-ethoxy-2-(ethoxycarbony...)
Affinity DataIC50:  3.20E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Defense Medical Center

LigandPNGBDBM11312(2-(4,5-dihydro-1,3-thiazol-2-yl)-1-(1,3-thiazol-2-...)
Affinity DataIC50:  4.00E+4nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed