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Found
60
Enz. Inhib. hit(s) with all data for entry = 50037812
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193999
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenyle...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194011
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N4,N4-dimethyl-N...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193989
(N-((S)-1-(4-fluorophenyl)ethyl)-2-(3H-imidazo[4,5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193995
(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194009
(6-(3,4-dimethoxyphenyl)-2-(3H-imidazo[4,5-c]pyridi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193995
(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193990
(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194015
(3-(4-(2-chlorophenoxy)-6-(4-methylpiperazin-1-yl)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193994
(4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194011
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N4,N4-dimethyl-N...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 19nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193991
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(4-methylpiper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 19nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194010
(6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193999
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenyle...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194015
(3-(4-(2-chlorophenoxy)-6-(4-methylpiperazin-1-yl)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194005
(N-((S)-1-(4-fluorophenyl)ethyl)-6-(furan-3-yl)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194008
(3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194008
(3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 31nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50132420
(CHEMBL2397013 | CHEMBL323994 | 3-((1H-pyrrol-2-yl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 38nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193994
(4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 42nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193993
(3-(4-((S)-1-methoxypropan-2-ylamino)pyrimidin-2-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 45nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194009
(6-(3,4-dimethoxyphenyl)-2-(3H-imidazo[4,5-c]pyridi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 49nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193987
(4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenyle...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 49nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193996
(2-(1H-imidazo[4,5-c]pyridin-1-yl)-N-((S)-1-phenyle...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193997
(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194004
(N-((S)-1-(4-chlorophenyl)ethyl)-2-(3H-imidazo[4,5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 51nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194000
(3-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 56nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194013
((R)-1-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 59nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193990
(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193991
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(4-methylpiper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 61nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194010
(6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 62nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194007
(3-(4-(2,6-difluorophenoxy)-6-(4-methylpiperazin-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 68nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194014
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(1-methyl-1H-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 77nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194005
(N-((S)-1-(4-fluorophenyl)ethyl)-6-(furan-3-yl)-2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 83nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193989
(N-((S)-1-(4-fluorophenyl)ethyl)-2-(3H-imidazo[4,5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 92nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194002
(N-(2-chlorophenyl)-2-(3H-imidazo[4,5-c]pyridin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 113nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194007
(3-(4-(2,6-difluorophenoxy)-6-(4-methylpiperazin-1-...)
Copy SMILES
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
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Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193993
(3-(4-((S)-1-methoxypropan-2-ylamino)pyrimidin-2-yl...)
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Affinity Data
IC50: 124nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
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PubMed
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Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194002
(N-(2-chlorophenyl)-2-(3H-imidazo[4,5-c]pyridin-3-y...)
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Affinity Data
IC50: 131nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
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PubMed
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Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193997
(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
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Affinity Data
IC50: 141nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
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PubMed
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Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193987
(4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenyle...)
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Affinity Data
IC50: 145nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194003
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-methyl-N-((S)-...)
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Affinity Data
IC50: 153nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193997
(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 165nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194006
(6-(3-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
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Affinity Data
IC50: 167nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
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PubMed
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Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194000
(3-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
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Affinity Data
IC50: 167nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
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PubMed
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Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194013
((R)-1-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-...)
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Affinity Data
IC50: 180nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194014
(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(1-methyl-1H-p...)
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Affinity Data
IC50: 245nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193997
(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Copy SMILES
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Affinity Data
IC50: 446nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50194006
(6-(3-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50132420
(CHEMBL2397013 | CHEMBL323994 | 3-((1H-pyrrol-2-yl)...)
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Affinity Data
IC50: 600nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Tyrosine-protein kinase JAK3
(Human)
Procter and Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50193996
(2-(1H-imidazo[4,5-c]pyridin-1-yl)-N-((S)-1-phenyle...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 700nM
Assay Description:
Inhibition of JAK3
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
12/9/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
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