Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50018305
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194233((+)-N-{(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.120nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194219((+)-(2R)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-me...)
Affinity DataIC50:  0.150nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194232((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.390nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194235((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.400nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194231((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.420nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194227((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.450nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194223((+)-1-(4-fluorophenyl)-N-[(1S,4R,5R,7S)-5-(3-hydro...)
Affinity DataIC50:  0.450nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194230((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.480nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194224((+)-N-{(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.5nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194228((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.680nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194234((+)-N-{(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.720nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194225((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  0.800nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194221((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  1.40nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194229((+)-2-ethyl-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4...)
Affinity DataIC50:  1.80nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194218((+)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl...)
Affinity DataIC50:  1.80nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194222((-)-N-(1S,4R,5R,7S)-{5-(3-hydroxy)phenyl-4-methyl-...)
Affinity DataIC50:  7.70nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194226((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50:  16nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001680((C3H5)2 Tyr-Aib-Aib-Phe-Leu | (H2C=CCH2)2-Tyr-Aib-...)
Affinity DataIC50:  83nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194220((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-2,4-dimet...)
Affinity DataIC50:  95nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed