Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 2606
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22564BDBM22564(2-{2-chloro-4-[3-(4-methyl-1,4-diazepan-1-yl)propo...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22563BDBM22563(2-{2-chloro-4-[3-(4-methyl-1,4-diazepan-1-yl)propo...)
Affinity DataKi:  9nM ΔG°:  -45.9kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22556BDBM22556(2-{2-chloro-4-[3-(4-methylpiperazin-1-yl)propoxy]p...)
Affinity DataKi:  22nM ΔG°:  -43.7kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22560BDBM22560(5-tert-butyl-2-{3-chloro-4-[3-(4-methyl-1,4-diazep...)
Affinity DataKi:  26nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22562BDBM22562(5-tert-butyl-2-{3-methyl-4-[3-(4-methylpiperazin-1...)
Affinity DataKi:  26nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22558BDBM22558(4-{2-chloro-4-[3-(4-methylpiperazin-1-yl)propoxy]p...)
Affinity DataKi:  28nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22555BDBM22555(2-{2-chloro-4-[3-(4-methylpiperazin-1-yl)propoxy]p...)
Affinity DataKi:  46nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22561BDBM22561(5-tert-butyl-2-{3-chloro-4-[3-(4-methylpiperazin-1...)
Affinity DataKi:  65nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22557BDBM22557(5-tert-butyl-2-{2-chloro-4-[3-(4-methylpiperazin-1...)
Affinity DataKi:  93nM ΔG°:  -40.1kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22565BDBM22565(5-chloro-2-{4-[3-(4-methylpiperazin-1-yl)propoxy]p...)
Affinity DataKi:  124nM ΔG°:  -39.4kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 22559BDBM22559(1-{3-[4-(5-tert-butyl-1H-1,3-benzodiazol-2-yl)-2-c...)
Affinity DataKi:  250nM ΔG°:  -37.7kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed