Compile Data Set for Download or QSAR
maximum 50k data
Found 56 Enz. Inhib. hit(s) with all data for entry = 50018406
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195377((4'-{[[1-(3-methyl-butyl)-piperidin-4-yl]-(4-penty...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195408(CHEMBL220689 | N-[4'-(benzylcarbamoyl-methyl)-biph...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195416(CHEMBL219994 | N-(2-dibutylamino-ethyl)-4-pentyl-N...)
Affinity DataIC50:  56nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195373(4'-{[(2-dibutylamino-ethyl)-(4-pentyl-benzoyl)-ami...)
Affinity DataIC50:  72nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195407(CHEMBL207616 | N-(2-dibutylamino-ethyl)-N-[4'-(2-m...)
Affinity DataIC50:  74nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195390(4'-{[(2-dibutylamino-ethyl)-(4-pentyl-benzoyl)-ami...)
Affinity DataIC50:  77nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195380(CHEMBL387315 | N-{4'-[(benzyl-methyl-carbamoyl)-me...)
Affinity DataIC50:  91nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195402(CHEMBL374329 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  101nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195372(CHEMBL220718 | N-biphenyl-4-ylmethyl-N-(2-dibutyla...)
Affinity DataIC50:  143nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195388(CHEMBL387316 | N-(4-((N-(2-(dibutylamino)ethyl)-4-...)
Affinity DataIC50:  154nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195415(CHEMBL375351 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  165nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195389((4'-{[(2-dibutylamino-ethyl)-(4-pentyl-benzoyl)-am...)
Affinity DataIC50:  183nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195423(CHEMBL219771 | N-(4-thiomorpholinobenzyl)-N-(2-(di...)
Affinity DataIC50:  188nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195422(CHEMBL375125 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195384(CHEMBL223243 | N-(4-(4-phenylpiperazin-1-yl)benzyl...)
Affinity DataIC50:  200nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195419(CHEMBL385329 | N-(4-((N-(2-(dibutylamino)ethyl)-4-...)
Affinity DataIC50:  202nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195412(CHEMBL375526 | N-(4-(pyridin-4-yl)benzyl)-N-(2-(di...)
Affinity DataIC50:  212nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195378(CHEMBL375169 | N-(4-(phenylamino)benzyl)-N-(2-(dib...)
Affinity DataIC50:  224nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195392(CHEMBL220370 | N-(4-(1H-pyrrol-1-yl)benzyl)-N-(2-(...)
Affinity DataIC50:  240nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195417(CHEMBL220277 | N-(4-((N-(2-(dibutylamino)ethyl)-4-...)
Affinity DataIC50:  243nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195393(CHEMBL375225 | N-(4-(benzyl(methyl)amino)benzyl)-N...)
Affinity DataIC50:  289nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195400(CHEMBL220562 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  334nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195404(CHEMBL223290 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  334nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195425(CHEMBL223843 | N-(4-(piperidin-1-yl)benzyl)-N-(2-(...)
Affinity DataIC50:  369nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195426(CHEMBL221151 | N-(4-(pyridin-3-yl)benzyl)-N-(2-(di...)
Affinity DataIC50:  374nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195374(CHEMBL222773 | N-(4-(pyridin-2-yl)benzyl)-N-(2-(di...)
Affinity DataIC50:  380nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195396(CHEMBL219717 | N-(4-(benzylamino)benzyl)-N-(2-(dib...)
Affinity DataIC50:  429nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195397(CHEMBL220369 | N-((6-(benzo[d][1,3]dioxol-5-yl)pyr...)
Affinity DataIC50:  437nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195386(CHEMBL220322 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  439nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195376((4'-{[(2-dibutylamino-ethyl)-(4-pentyl-benzoyl)-am...)
Affinity DataIC50:  463nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195379(CHEMBL221150 | N-(4-((N-(2-(dibutylamino)ethyl)-4-...)
Affinity DataIC50:  464nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195398(CHEMBL220942 | N-(2-dibutylamino-ethyl)-N-[4'-(2-h...)
Affinity DataIC50:  511nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195406(CHEMBL220667 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  531nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195383(CHEMBL221149 | N-(4-(pyrimidin-5-yl)benzyl)-N-(2-(...)
Affinity DataIC50:  531nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195418(CHEMBL375310 | N-(4-(methyl(phenyl)amino)benzyl)-N...)
Affinity DataIC50:  574nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195409(CHEMBL220331 | N-(2-(dibutylamino)ethyl)-4-pentyl-...)
Affinity DataIC50:  587nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195381(CHEMBL374456 | N-(2-(dibutylamino)ethyl)-4-pentyl-...)
Affinity DataIC50:  589nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195427(CHEMBL273338 | N-(2-(dibutylamino)ethyl)-4-pentyl-...)
Affinity DataIC50:  642nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195413(CHEMBL223345 | N-(4-(4-benzylpiperazin-1-yl)benzyl...)
Affinity DataIC50:  646nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195411(CHEMBL436306 | N-(4-(1H-indol-1-yl)benzyl)-N-(2-(d...)
Affinity DataIC50:  670nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195375(CHEMBL387156 | N-(2-(dibutylamino)ethyl)-4-pentyl-...)
Affinity DataIC50:  736nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195421(CHEMBL219776 | N-(4-(diethylamino)benzyl)-N-(2-(di...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195399(CHEMBL222895 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195405(CHEMBL373671 | N-(4-(benzo[d][1,3]dioxol-5-yl)benz...)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195395(CHEMBL221276 | N-(1-benzylpiperidin-4-yl)-4-pentyl...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195414(CHEMBL375835 | N-(4-(pyridin-4-ylamino)benzyl)-N-(...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195410(CHEMBL222722 | N-((5-(benzo[d][1,3]dioxol-5-yl)pyr...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195401(CHEMBL434748 | N-(2-(dibutylamino)ethyl)-4-pentyl-...)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195403(CHEMBL424758 | N-(2-(dibutylamino)ethyl)-4-pentyl-...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195391(CHEMBL220516 | N-(4-(4-methylpiperazin-1-yl)benzyl...)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of PM2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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