Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 2128
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17217(2,6-quinolinyl derivative, 39 | 2-[(2-chloro-4-met...)
Affinity DataIC50:  3.5nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17216(2,6-quinolinyl derivative, 38 | 2-[(2-chloro-6-met...)
Affinity DataIC50:  3.90nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17203(2,6-quinolinyl derivative, 25 | 3-[2-(2-chloro-6-n...)
Affinity DataIC50:  6.5nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17220(2,6-quinolinyl derivative, 42 | 2-{[1-(4-chlorophe...)
Affinity DataIC50:  6.60nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17207(2,6-quinolinyl derivative, 29 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  7.30nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17197(2,6-quinolinyl derivative, 19 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  7.80nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17218(2,6-quinolinyl derivative, 40 | 2-[(2,4-dichloro-6...)
Affinity DataIC50:  7.90nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17210(2,6-quinolinyl derivative, 32 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  8.60nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17221(2,6-quinolinyl derivative, 43 | 2-{[(2S)-1-benzyl-...)
Affinity DataIC50:  15.3nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17202(2,6-quinolinyl derivative, 24 | 3-[2-(2-chloro-6-f...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17198(2,6-quinolinyl derivative, 20 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17214(2,6-quinolinyl derivative, 36 | 3-[2-(2,6-dichloro...)
Affinity DataIC50:  37.2nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17213(2,6-quinolinyl derivative, 35 | 3-[2-(2,6-dichloro...)
Affinity DataIC50:  53.7nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17206(2,6-quinolinyl derivative, 28 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  92nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17201(2,6-quinolinyl derivative, 23 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  102nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17205(2,6-quinolinyl derivative, 27 | 3-[2-(2-bromopheny...)
Affinity DataIC50:  154nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17212(2,6-quinolinyl derivative, 34 | 3-{2-[2-chloro-5-(...)
Affinity DataIC50:  209nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17200(2,6-quinolinyl derivative, 22 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  372nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17209(2,6-quinolinyl derivative, 31 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  381nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17215(2,6-quinolinyl derivative, 37 | 3-[2-(2,6-dichloro...)
Affinity DataIC50:  435nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17199(2,6-quinolinyl derivative, 21 | 2-[(2,6-dichloroph...)
Affinity DataIC50:  748nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17219(2,6-quinolinyl derivative, 41 | 3-[2-(2,6-dichloro...)
Affinity DataIC50:  5.64E+3nMpH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17208(2,6-quinolinyl derivative, 30 | 2-[(2,6-dichloroph...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17211(2,6-quinolinyl derivative, 33 | 2-[(2,6-dichloroph...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1 [T112H](Homo sapiens (Human))
Ucb Pharma

LigandPNGBDBM17204(2,6-quinolinyl derivative, 26 | 2-[(2,6-dichloroph...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The VLA-4 expressing U937 cells were plated in 96-well microtiter plates, precoated with soluble human recombinant VCAM-1, in the presence of test co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed