Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50018697
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198223(5-(1-(2-(4-(pyridin-2-yl)benzylamino)ethyl)-1H-pyr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198204(5-(1-(2-((1H-indol-5-yl)methylamino)ethyl)-1H-pyra...)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198215(N-hydroxy-5-(1-(2-((1-methyl-1H-indol-2-yl)methyla...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198208(5-(1-(2-(3-chlorophenylamino)-2-oxoethyl)-1H-pyraz...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198211(N-hydroxy-5-(1-(2-oxo-2-(quinolin-8-ylamino)ethyl)...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198202(5-(1-(2-(3,5-difluorophenylamino)-2-oxoethyl)-1H-p...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198224(N-hydroxy-5-(1-(2-(2-methoxyphenylamino)-2-oxoethy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198201(5-(1-(2-(4-(1H-imidazol-1-yl)benzylamino)ethyl)-1H...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198205(5-(1-(2-(benzofuran-5-ylmethylamino)ethyl)-1H-pyra...)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198207(5-(1-(2-(1H-indol-7-ylamino)-2-oxoethyl)-1H-pyrazo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198216(5-(1-(2-(4-methoxybenzylamino)ethyl)-1H-pyrazol-3-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198212(5-(1-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)-1H...)
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198210(5-(1-(2-(benzyloxy)ethyl)-1H-pyrazol-3-yl)-N-hydro...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198206(N-hydroxy-5-(1-(2-oxo-2-(phenylamino)ethyl)-1H-pyr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198213(N-hydroxy-5-(1-(2-phenoxyethyl)-1H-pyrazol-3-yl)th...)
Affinity DataIC50: 22nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198218(ADS-102550 | 5-(1-(2-(benzo[d][1,3]dioxol-5-ylmeth...)
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198219(5-(1-(2-(benzylamino)ethyl)-1H-pyrazol-3-yl)-N-hyd...)
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198220(N-hydroxy-5-(1-(3-phenylpropyl)-1H-pyrazol-3-yl)th...)
Affinity DataIC50: 34nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198214(N-hydroxy-5-(1-(2-((2-phenylpyrimidin-5-yl)methyla...)
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198217(N-hydroxy-5-(1-(2-(phenethylamino)ethyl)-1H-pyrazo...)
Affinity DataIC50: 69nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198222(N-hydroxy-5-(1-phenethyl-1H-pyrazol-3-yl)thiophene...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198203(5-(1-(2-(3,4-dimethoxybenzylamino)ethyl)-1H-pyrazo...)
Affinity DataIC50: 107nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 125nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198209(5-(1-benzyl-1H-pyrazol-3-yl)-N-hydroxythiophene-2-...)
Affinity DataIC50: 153nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198221(ADS-100380 | N-hydroxy-5-(1-methyl-3-(trifluoromet...)
Affinity DataIC50: 750nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed