Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50018734
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198484(5-(5-((2-(benzofuran-4-yl)ethylamino)methyl)pyridi...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198461(5-(5-((2-chlorophenethylamino)methyl)pyridin-2-yl)...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198480(5-(5-((2-chlorobenzylamino)methyl)pyridin-2-yl)-N-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198462(5-(5-((biphenyl-4-ylmethylamino)methyl)pyridin-2-y...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198475(5-(5-((benzo[d][1,3]dioxol-5-ylmethylamino)methyl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198469(N-hydroxy-5-(5-((2-methylphenethylamino)methyl)pyr...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198473(5-(5-((2-(1H-indol-3-yl)ethylamino)methyl)pyridin-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198478(5-(5-(2-(benzylamino)ethyl)pyridin-2-yl)-N-hydroxy...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198454(5-(5-((4-chlorobenzylamino)methyl)pyridin-2-yl)-N-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198470(N-hydroxy-5-(5-((3-methylphenethylamino)methyl)pyr...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198472(5-(5-(2-(benzo[d][1,3]dioxol-5-ylmethylamino)ethyl...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198463(5-(5-((4-fluorophenethylamino)methyl)pyridin-2-yl)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198465(N-hydroxy-5-(5-((2-phenoxyethylamino)methyl)pyridi...)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198453(5-(5-(((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198466(5-(5-((2-fluorophenethylamino)methyl)pyridin-2-yl)...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198455(N-hydroxy-5-(5-((phenethylamino)methyl)pyridin-2-y...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198464(5-(5-(2-(4-fluorobenzylamino)ethyl)pyridin-2-yl)-N...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198468(N-hydroxy-5-(5-((4-methylphenethylamino)methyl)pyr...)
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198474(N-hydroxy-5-(5-((phenylamino)methyl)pyridin-2-yl)t...)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198483(5-(5-((benzylamino)methyl)pyridin-2-yl)-N-hydroxyt...)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198458(N-hydroxy-5-(5-((2-methoxyphenethylamino)methyl)py...)
Affinity DataIC50: 17nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198456(N-hydroxy-5-(5-((3-phenylpropylamino)methyl)pyridi...)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198218(ADS-102550 | 5-(1-(2-(benzo[d][1,3]dioxol-5-ylmeth...)
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198482(5-(5-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)pyri...)
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198471(N-hydroxy-5-(5-(2-(phenethylamino)ethyl)pyridin-2-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198459(5-(5-((benzyl(methyl)amino)methyl)pyridin-2-yl)-N-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198457(N-hydroxy-5-(5-(phenethylamino)pyridin-2-yl)thioph...)
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 125nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198476(N-hydroxy-5-(pyrimidin-2-yl)thiophene-2-carboxamid...)
Affinity DataIC50: 186nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198477(N-hydroxy-5-(pyridin-2-yl)thiophene-2-carboxamide ...)
Affinity DataIC50: 243nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198460(5-(6-((benzylamino)methyl)pyridin-2-yl)-N-hydroxyt...)
Affinity DataIC50: 359nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198467(N-hydroxy-5-(6-((phenethylamino)methyl)pyridin-2-y...)
Affinity DataIC50: 581nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198221(ADS-100380 | N-hydroxy-5-(1-methyl-3-(trifluoromet...)
Affinity DataIC50: 750nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198486(N-hydroxy-5-phenylthiophene-2-carboxamide | CHEMBL...)
Affinity DataIC50: 900nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198485(N-hydroxy-5-(pyridin-3-yl)thiophene-2-carboxamide ...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198481(N-hydroxy-5-(pyridin-4-yl)thiophene-2-carboxamide ...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198479(N-hydroxy-2,2'-bithiophene-5-carboxamide | CHEMBL2...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198483(5-(5-((benzylamino)methyl)pyridin-2-yl)-N-hydroxyt...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198218(ADS-102550 | 5-(1-(2-(benzo[d][1,3]dioxol-5-ylmeth...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of CYP450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed