Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50018735
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241095((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  7.40nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198501((S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)
Affinity DataKi:  11nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198502((S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)
Affinity DataKi:  12nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198499((S)-4-(5-chloropyridin-2-yl)-N-(6-((dimethylamino)...)
Affinity DataKi:  18nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198495((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  20nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198500((S)-N-(6-(((2-(dimethylamino)-2-oxoethyl)(methyl)a...)
Affinity DataKi:  24nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198494((S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataKi:  103nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198490((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  118nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)
Affinity DataKi:  129nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198498((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  140nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198504((S)-4'-fluoro-N-methyl-N-(6-((3-oxopiperazin-1-yl)...)
Affinity DataKi:  145nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198491((S)-1-(((S)-6-(4'-fluoro-N-methylbiphenyl-4-ylcarb...)
Affinity DataKi:  146nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198493((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  184nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198487((S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataKi:  302nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198489((S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataKi:  727nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198492(CHEMBL217860 | N-[(2S)-6-[(1,1-dioxo-1,4-thiomorph...)
Affinity DataKi:  755nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198503((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  890nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198488((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataKi:  2.48E+3nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198497((S)-6-(4-fluorophenyl)-N-methyl-N-(6-((3-oxopipera...)
Affinity DataKi:  3.47E+3nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198500((S)-N-(6-(((2-(dimethylamino)-2-oxoethyl)(methyl)a...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241095((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198501((S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198491((S)-1-(((S)-6-(4'-fluoro-N-methylbiphenyl-4-ylcarb...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198502((S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198495((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198502((S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198493((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198499((S)-4-(5-chloropyridin-2-yl)-N-(6-((dimethylamino)...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198493((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198495((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198490((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198490((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198499((S)-4-(5-chloropyridin-2-yl)-N-(6-((dimethylamino)...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198498((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241095((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198501((S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198489((S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198498((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198500((S)-N-(6-(((2-(dimethylamino)-2-oxoethyl)(methyl)a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198496(CHEMBL217501 | N-[(2S)-6-[(1,1-dioxo-1,4-thiomorph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198491((S)-1-(((S)-6-(4'-fluoro-N-methylbiphenyl-4-ylcarb...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198497((S)-6-(4-fluorophenyl)-N-methyl-N-(6-((3-oxopipera...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198492(CHEMBL217860 | N-[(2S)-6-[(1,1-dioxo-1,4-thiomorph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198494((S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198504((S)-4'-fluoro-N-methyl-N-(6-((3-oxopiperazin-1-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198487((S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198503((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198488((S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed