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Found 13 Enz. Inhib. hit(s) with all data for entry = 50018738
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198569((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phe...)
Affinity DataIC50:  16nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198560((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-thiophen-3-yl-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198564((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-pyridin-3-yl-2...)
Affinity DataIC50:  28nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198561((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-pyrimidin-5-yl...)
Affinity DataIC50:  53nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198562((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-thiophen-2-yl-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198566((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-m-tolyl-2,3,6,...)
Affinity DataIC50:  68nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198565((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-phenyl-2,3,6,7...)
Affinity DataIC50:  91nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198567((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-nitro-pheny...)
Affinity DataIC50:  122nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198563((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-chloro-phen...)
Affinity DataIC50:  134nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198570((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(3-chloro-phen...)
Affinity DataIC50:  141nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198568((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-butyl-pheny...)
Affinity DataIC50:  152nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Inserm U761 Biostructures And Drug Discovery Lille

Curated by ChEMBL
LigandPNGBDBM50198559((6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-(4-trifluorome...)
Affinity DataIC50:  377nMAssay Description:Inhibition of bovine PDE5 after 24 hrs by HTRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed