Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50018874
TargetLiver carboxylesterase(Sus scrofa)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50022772(CHEMBL1025 | Diisopropoxyphosphoryl fluoride | Dii...)
Affinity DataIC50:  50nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal protective protein(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant CatA using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human leukocyte elastase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal protective protein(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50022772(CHEMBL1025 | Diisopropoxyphosphoryl fluoride | Dii...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant CatA using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase(Sus scrofa)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal protective protein(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant CatA using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human leukocyte elastase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase(Sus scrofa)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed