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Found 21 Enz. Inhib. hit(s) with all data for entry = 50018938
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human ACAT1 expressed in AC29 cells by cell-based fluorescent assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human ACAT2 expressed in AC29 cells by cell-based fluorescent assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033725((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033725((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033728((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  3.07E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033739((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  4.96E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033710((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  5.37E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033710((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  5.62E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033722((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  5.75E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)
Affinity DataIC50:  7.04E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033728((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  7.14E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033739((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  7.76E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033733((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  8.45E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033733((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  9.48E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033741((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.12E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033741((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200395((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200395((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.87E+5nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed