Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 1674
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13211((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...)
Affinity DataKi:  25nM ΔG°:  -43.0kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13212((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...)
Affinity DataKi:  61nM ΔG°:  -40.8kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13213((3S,6S,9aS)-6-[(2S)-2-(dimethylamino)butanamido]-N...)
Affinity DataKi:  1.44E+4nM ΔG°:  -27.4kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University of Michigan

LigandPNGBDBM13214((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-hydroxypr...)
Affinity DataKi:  2.90E+4nM ΔG°:  -25.6kJ/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed