Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50019205
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202681(7-fluoro-4-oxo-N-(1-((2-oxo-2H-chromen-7-yl)methyl...)
Affinity DataIC50: 1nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202682(7-fluoro-N-(1-((1-methyl-2-oxo-1,2-dihydroquinolin...)
Affinity DataIC50: 3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202677(N-(1-(benzo[b]thiophen-5-ylmethyl)piperidin-4-yl)-...)
Affinity DataIC50: 4nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202687(N-(1-((1H-indol-6-yl)methyl)piperidin-4-yl)-7-fluo...)
Affinity DataIC50: 5nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202675(7-fluoro-4-oxo-N-(1-((2-oxo-1,2-dihydroquinolin-7-...)
Affinity DataIC50: 7nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202684(N-(1-(benzofuran-5-ylmethyl)piperidin-4-yl)-7-fluo...)
Affinity DataIC50: 7nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202683(N-(1-(benzo[d]oxazol-6-ylmethyl)piperidin-4-yl)-7-...)
Affinity DataIC50: 10nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202686(7-fluoro-4-oxo-N-(1-((3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50: 19nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202678(N-(1-((1H-indol-5-yl)methyl)piperidin-4-yl)-7-fluo...)
Affinity DataIC50: 38nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202676(7-fluoro-4-oxo-N-(1-((2-oxo-2,3-dihydrobenzo[d]oxa...)
Affinity DataIC50: 43nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202674(N-(1-(3-acetamidobenzyl)piperidin-4-yl)-7-fluoro-4...)
Affinity DataIC50: 47nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202673(N-(1-((2-ethylbenzo[d]oxazol-5-yl)methyl)piperidin...)
Affinity DataIC50: 95nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202680(7-fluoro-4-oxo-N-(1-((3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50: 166nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202679(N-(1-((2-ethylbenzo[d]oxazol-6-yl)methyl)piperidin...)
Affinity DataIC50: 1.27E+3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202677(N-(1-(benzo[b]thiophen-5-ylmethyl)piperidin-4-yl)-...)
Affinity DataIC50: 1.37E+3nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202685(7-fluoro-4-oxo-N-(1-((2-oxobenzo[d][1,3]dioxol-5-y...)
Affinity DataIC50: 2.01E+3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202687(N-(1-((1H-indol-6-yl)methyl)piperidin-4-yl)-7-fluo...)
Affinity DataIC50: 2.53E+3nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202684(N-(1-(benzofuran-5-ylmethyl)piperidin-4-yl)-7-fluo...)
Affinity DataIC50: 5.28E+3nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202686(7-fluoro-4-oxo-N-(1-((3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50: 5.79E+3nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202678(N-(1-((1H-indol-5-yl)methyl)piperidin-4-yl)-7-fluo...)
Affinity DataIC50: 6.08E+3nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 1.51E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202673(N-(1-((2-ethylbenzo[d]oxazol-5-yl)methyl)piperidin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202676(7-fluoro-4-oxo-N-(1-((2-oxo-2,3-dihydrobenzo[d]oxa...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202679(N-(1-((2-ethylbenzo[d]oxazol-6-yl)methyl)piperidin...)
Affinity DataIC50: 2.67E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202683(N-(1-(benzo[d]oxazol-6-ylmethyl)piperidin-4-yl)-7-...)
Affinity DataIC50: 3.46E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202682(7-fluoro-N-(1-((1-methyl-2-oxo-1,2-dihydroquinolin...)
Affinity DataIC50: 4.74E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197141(N-[1-N-[1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl...)
Affinity DataIC50: 4.77E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202681(7-fluoro-4-oxo-N-(1-((2-oxo-2H-chromen-7-yl)methyl...)
Affinity DataIC50: 5.11E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202674(N-(1-(3-acetamidobenzyl)piperidin-4-yl)-7-fluoro-4...)
Affinity DataIC50: 6.07E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202685(7-fluoro-4-oxo-N-(1-((2-oxobenzo[d][1,3]dioxol-5-y...)
Affinity DataIC50: 8.52E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202675(7-fluoro-4-oxo-N-(1-((2-oxo-1,2-dihydroquinolin-7-...)
Affinity DataIC50: 8.55E+4nMAssay Description:Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed