Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50019236
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130275BDBM50130275(4-{3-[2-(dimethylamino)ethyl]-1H-indole-1-sulfonyl...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203141BDBM50203141(N,N-dimethyl(9-(phenylsulfonyl)-2,3,4,9-tetrahydro...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203128BDBM50203128(N,N-dimethyl-2-(1-(4-(trifluoromethyl)phenylsulfon...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203140BDBM50203140(N,N-dimethyl-2-(1-tosyl-1H-indol-3-yl)ethanamine |...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106250BDBM50106250([2-(1-Benzenesulfonyl-1H-indol-3-yl)-ethyl]-dimeth...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50164758BDBM50164758([2-(1-Benzyl-1H-indol-3-yl)-ethyl]-dimethyl-amine ...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203145BDBM50203145(2-(1-(4-methoxyphenylsulfonyl)-1H-indol-3-yl)-N,N-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203133BDBM50203133(2-(1-(4-chlorobenzyl)-1H-indol-3-yl)-N,N-dimethyle...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203143BDBM50203143(dimethyl-{2-[1-(4-methyl-benzyl)-1H-indol-3-yl]-et...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203139BDBM50203139(4-(5,6,7,8-tetrahydrocarbazol-9-ylsulfonyl)benzena...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203142BDBM50203142(4-((3-(2-(dimethylamino)ethyl)-1H-indol-1-yl)methy...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203136BDBM50203136(2-(1-(4-chlorophenylsulfonyl)-1H-indol-3-yl)-N,N-d...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203144BDBM50203144(2-(1-(4-methoxybenzyl)-1H-indol-3-yl)-N,N-dimethyl...)
Affinity DataKi:  132nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203129BDBM50203129(2-(1-(butylsulfonyl)-1H-indol-3-yl)-N,N-dimethylet...)
Affinity DataKi:  135nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50143488BDBM50143488((9-benzyl-2,3,4,9-tetrahydro-1H-carbazol-4-yl)-N,N...)
Affinity DataKi:  136nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203127BDBM50203127(2-(1-(cyclohexylsulfonyl)-1H-indol-3-yl)-N,N-dimet...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203131BDBM50203131(N,N-dimethyl-2-(1-(pentylsulfonyl)-1H-indol-3-yl)e...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203135BDBM50203135(N,N-dimethyl-2-(1-(propylsulfonyl)-1H-indol-3-yl)e...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203138BDBM50203138(N,N-dimethyl-2-(1-(octylsulfonyl)-1H-indol-3-yl)et...)
Affinity DataKi:  440nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203137BDBM50203137(2-(1-(4-(trifluoromethyl)benzyl)-1H-indol-3-yl)-N,...)
Affinity DataKi:  445nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203130BDBM50203130(2-(1-(isopropylsulfonyl)-1H-indol-3-yl)-N,N-dimeth...)
Affinity DataKi:  590nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203134BDBM50203134(4-((5,6,7,8-tetrahydrocarbazol-9-yl)methyl)benzena...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203132BDBM50203132(4-((1H-indol-1-yl)methyl)benzenamine | CHEMBL24728...)
Affinity DataKi:  8.20E+3nMAssay Description:Displacement of [3H] LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed