Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50038013
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203558(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203561((4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203553(CHEMBL247664 | N-(2-amino-2-methylpropyl)-4-((6,7-...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203559(2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203557(3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203562(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203556(6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzof...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203554(2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)me...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203563(6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203560(8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203565(6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)ben...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203555(6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-y...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203558(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203556(6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzof...)
Affinity DataKi:  135nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203553(CHEMBL247664 | N-(2-amino-2-methylpropyl)-4-((6,7-...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203559(2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203561((4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203559(2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl...)
Affinity DataKi:  204nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203557(3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-...)
Affinity DataKi:  216nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203554(2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)me...)
Affinity DataKi:  299nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203563(6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)...)
Affinity DataKi:  304nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203556(6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzof...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203560(8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203560(8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203562(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  454nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203557(3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-...)
Affinity DataKi:  584nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203555(6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-y...)
Affinity DataKi:  752nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203565(6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)ben...)
Affinity DataKi:  804nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203554(2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)me...)
Affinity DataKi:  857nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203558(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  857nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203563(6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)...)
Affinity DataKi:  949nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203561((4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl...)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203553(CHEMBL247664 | N-(2-amino-2-methylpropyl)-4-((6,7-...)
Affinity DataKi:  1.54E+3nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203555(6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-y...)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203562(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203565(6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)ben...)
Affinity DataKi:  2.55E+3nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed