Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50019346
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203772((E)-5-[1-(4-cetyloxy-3-methoxyphenyl)-1-phenylmeth...)
Affinity DataIC50:  2.96E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50411244(CHEMBL2113260)
Affinity DataIC50:  3.44E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203775((Z)-5-[1-(4-cetyloxy-3-methoxyphenyl)-1-phenylmeth...)
Affinity DataIC50:  3.57E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203771(5-(4-carboxy-2-(2,4-dioxo-4-(4-stearamidophenyl)bu...)
Affinity DataIC50:  3.59E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203775((Z)-5-[1-(4-cetyloxy-3-methoxyphenyl)-1-phenylmeth...)
Affinity DataIC50:  4.28E+3nMAssay Description:Antagonist activity against human S1P1 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203773(5-(4-carboxy-2-(4-(4-(heptadecylamino)phenyl)-2,4-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50411244(CHEMBL2113260)
Affinity DataIC50:  6.18E+3nMAssay Description:Antagonist activity against human S1P1 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203772((E)-5-[1-(4-cetyloxy-3-methoxyphenyl)-1-phenylmeth...)
Affinity DataIC50:  6.64E+3nMAssay Description:Antagonist activity against human S1P1 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203778(2-(hexadecyloxy)-5-sulfobenzoic acid | CHEMBL38725...)
Affinity DataIC50:  8.75E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203764((4R)-2-(3-heptylphenyl)thiazolidine-4-carboxylic a...)
Affinity DataIC50:  9.70E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203765((E)-5-[1-(4-cetyloxyphenyl)-1-phenylmethylene]sulf...)
Affinity DataIC50:  9.74E+3nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203777((E)-5-[1-(4-octyloxy-3-methoxyphenyl)-1-phenylmeth...)
Affinity DataIC50:  1.14E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203774((4R)-2-undecylthiazolidine-4-carboxylic acid | CHE...)
Affinity DataIC50:  1.16E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203767((4R)-2-(4-heptylphenyl)thiazolidine-4-carboxylic a...)
Affinity DataIC50:  1.31E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203776((Z)-5-[1-(4-octyloxy-3-methoxyphenyl)-1-phenylmeth...)
Affinity DataIC50:  1.32E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203770((4R)-2-decylthiazolidine-4-carboxylic acid | CHEMB...)
Affinity DataIC50:  1.57E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203769((4R)-2-(3-nonylphenyl)thiazolidine-4-carboxylic ac...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50203766((4R)-2-(3-((4-chloro-2-isopropyl-6-methylphenoxy)m...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity against human S1P3 receptor assessed as inhibition of S1P-induced intracellular calcium mobilization in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed