Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50037879
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 14.5nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 18.3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 19.7nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 19.8nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 23.4nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 40.3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204000((+/-)-1-[3-(4-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 52.2nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203998((+/-)-1-[3-(5-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 52.7nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203999((+/-)-1-[3-(20-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 98.6nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203997((+/-)-1-[2-(4-fluorophenyl)-2-(1-methylpiperidin-4...)
Affinity DataIC50: 333nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 423nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 482nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 491nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 543nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 723nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 729nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 805nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 820nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 877nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 953nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 2.14E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 2.83E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 3.13E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 3.94E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 3.94E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed