Compile Data Set for Download or QSAR
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Found 46 Enz. Inhib. hit(s) with all data for entry = 50037879
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  14.5nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  18.3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50:  19.7nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  19.8nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  23.4nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50:  40.3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50204000((+/-)-1-[3-(4-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  52.2nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203998((+/-)-1-[3-(5-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  52.7nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203999((+/-)-1-[3-(20-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  98.6nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203997((+/-)-1-[2-(4-fluorophenyl)-2-(1-methylpiperidin-4...)
Affinity DataIC50:  333nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50:  423nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  482nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  491nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  543nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  723nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  729nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  805nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  820nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50:  877nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50:  953nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50:  1.18E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  2.14E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50:  2.83E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  3.13E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50:  3.94E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50:  3.94E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203992((+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203994((+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203996((+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed