Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 1982
TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM15781(3-N-benzylpyridine-2,3-diamine | 3-Substituted 2-A...)
Affinity DataIC50:  3.10E+5nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM15789((2S)-1-(2,5-dimethylphenoxy)-3-(morpholin-4-yl)pro...)
Affinity DataIC50: >1.00E+6nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DatapH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM15788(4-[(4-fluorophenyl)methyl]piperidine | CHEMBL12043...)
Affinity DatapH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM14320(1-amino-isoquinoline | CHEMBL62083 | Fragment 17 |...)
Affinity DatapH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair