Compile Data Set for Download or QSAR
Report error Found 268 Enz. Inhib. hit(s) with all data for entry = 50019588
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205875BDBM50205875((R)-8-ethyl-7-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataEC50:  1.40nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205900BDBM50205900((R)-7-chloro-10-methoxy-1,3,4,10b-tetrahydropyrazi...)
Affinity DataEC50:  5nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205871BDBM50205871((R)-9-methyl-1,3,4,10b-tetrahydro-7-trifluoromethy...)
Affinity DataEC50:  6nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205861BDBM50205861((R)-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205861BDBM50205861((R)-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino...)
Affinity DataEC50:  7nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205875BDBM50205875((R)-8-ethyl-7-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataEC50:  8nMAssay Description:Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205871BDBM50205871((R)-9-methyl-1,3,4,10b-tetrahydro-7-trifluoromethy...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205889BDBM50205889((R)-9-methoxy-1,3,4,10b-tetrahydro-7-trifluorometh...)
Affinity DataEC50:  11nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205872BDBM50205872((R)-8-chloro-7-methoxy-1,3,4,10b-tetrahydropyrazin...)
Affinity DataEC50:  12nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205856BDBM50205856((R)-9-cyclopropyl-1,3,4,10b-tetrahydro-7-trifluoro...)
Affinity DataEC50:  14nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  15nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205882BDBM50205882((R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethyl...)
Affinity DataEC50:  16nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205858BDBM50205858((R)-9-ethyl-8-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataEC50:  17nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205877BDBM50205877((4S,10bR)-4-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataEC50:  18nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205875BDBM50205875((R)-8-ethyl-7-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205864BDBM50205864((+/-)-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazi...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205901BDBM50205901((R)-7,8-dichloro-1,3,4,10b-tetrahydropyrazino[2,1-...)
Affinity DataEC50:  20nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205895BDBM50205895((+/-)-1,3,4,10b-tetrahydro-7-trifluoromethoxypyraz...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205882BDBM50205882((R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205877BDBM50205877((4S,10bR)-4-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205899BDBM50205899((1S,10bR)-1-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataEC50:  22nMAssay Description:Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205899BDBM50205899((1S,10bR)-1-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205864BDBM50205864((+/-)-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazi...)
Affinity DataEC50:  24nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205895BDBM50205895((+/-)-1,3,4,10b-tetrahydro-7-trifluoromethoxypyraz...)
Affinity DataEC50:  26nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205899BDBM50205899((1S,10bR)-1-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataEC50:  28nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205872BDBM50205872((R)-8-chloro-7-methoxy-1,3,4,10b-tetrahydropyrazin...)
Affinity DataEC50:  28nMAssay Description:Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205899BDBM50205899((1S,10bR)-1-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205888BDBM50205888((R)-9-(1-methylcyclopropyl)-1,3,4,10b-tetrahydro-7...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205877BDBM50205877((4S,10bR)-4-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205870BDBM50205870((+/-)-7-chloro-1,3,4,10b-tetrahydropyrazino[2,1-a]...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205858BDBM50205858((R)-9-ethyl-8-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataEC50:  33nMAssay Description:Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205888BDBM50205888((R)-9-(1-methylcyclopropyl)-1,3,4,10b-tetrahydro-7...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205856BDBM50205856((R)-9-cyclopropyl-1,3,4,10b-tetrahydro-7-trifluoro...)
Affinity DataKi:  35nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205859BDBM50205859((R)-10-chloro-1,3,4,10b-tetrahydro-7-trifluorometh...)
Affinity DataEC50:  35nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205858BDBM50205858((R)-9-ethyl-8-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205870BDBM50205870((+/-)-7-chloro-1,3,4,10b-tetrahydropyrazino[2,1-a]...)
Affinity DataEC50:  37nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205875BDBM50205875((R)-8-ethyl-7-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205889BDBM50205889((R)-9-methoxy-1,3,4,10b-tetrahydro-7-trifluorometh...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205867BDBM50205867((+/-)-7-methylthio-1,3,4,10b-tetrahydropyrazino[2,...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205877BDBM50205877((4S,10bR)-4-methyl-1,3,4,10b-tetrahydro-7-trifluor...)
Affinity DataEC50:  40nMAssay Description:Activity at human 5HT2B expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205867BDBM50205867((+/-)-7-methylthio-1,3,4,10b-tetrahydropyrazino[2,...)
Affinity DataEC50:  42nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205875BDBM50205875((R)-8-ethyl-7-methoxy-1,3,4,10b-tetrahydropyrazino...)
Affinity DataKi:  43nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205862BDBM50205862((R)-9-ethenyl-1,3,4,10b-tetrahydro-7-trifluorometh...)
Affinity DataEC50:  43nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205862BDBM50205862((R)-9-ethenyl-1,3,4,10b-tetrahydro-7-trifluorometh...)
Affinity DataKi:  43nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205865BDBM50205865((R)-7-chloro-10-ethyl-1,3,4,10b-tetrahydropyrazino...)
Affinity DataEC50:  46nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205898BDBM50205898((R)-9-propyl-1,3,4,10b-tetrahydro-7-trifluoromethy...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205891BDBM50205891((R)-7-chloro-9-ethyl-1,3,4,10b-tetrahydropyrazino[...)
Affinity DataEC50:  49nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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