Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50019621
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206281(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  7nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50:  7nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206272(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  15nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206279(5-chloro-4-(1H-indol-6-yl)-N-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50:  16nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206285(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  19nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206271(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  26nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  33nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50:  37nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206281(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  48nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50:  69nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206278(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  76nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206284(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  103nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  148nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50:  159nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206273(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  216nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206274(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  314nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206270(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  334nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50:  348nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50:  439nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206270(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  455nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50:  461nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206273(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  540nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50:  687nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206274(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  781nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50:  797nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206271(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  808nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206284(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  847nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206285(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206279(5-chloro-4-(1H-indol-6-yl)-N-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206278(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206272(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed