Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50038457
TargetSolute carrier family 22 member 12(Human)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 22 member 12(Human)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataKi:  5.74E+3nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cells by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Rat)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human URAT1-mediated urate uptake in rat renal brush border membrane vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
The Chinese University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50026604(1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed