Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50019701
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50131622(4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-1-(4-methan...)
Affinity DataIC50: 90nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50131593(cimicoxib | 4-[4-Chloro-5-(3-fluoro-4-methoxy-phen...)
Affinity DataIC50: 100nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50131593(cimicoxib | 4-[4-Chloro-5-(3-fluoro-4-methoxy-phen...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50131622(4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-1-(4-methan...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206929(2-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 6.90E+3nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206928(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.40E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206927(3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imid...)
Affinity DataIC50: 1.60E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206930(4-{4-chloro-5-[3-fluoro-4-(2-hydroxyethoxy)phenyl]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206933(3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imid...)
Affinity DataIC50: 2.90E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206925(2-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 5.60E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206931(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 7.60E+4nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206932(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206929(2-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206928(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206933(3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206925(2-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206926(4-{4-chloro-5-[3-fluoro-4-(2-hydroxypropoxy)phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206927(3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206932(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206930(4-{4-chloro-5-[3-fluoro-4-(2-hydroxyethoxy)phenyl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206931(3-{4-[4-chloro-1-(4-(methylsulfonyl)phenyl)-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as TxB2 production after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206926(4-{4-chloro-5-[3-fluoro-4-(2-hydroxypropoxy)phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed